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The global climate is undergoing unprecedented changes, posing significant threats to species persistence. However, the spatiotemporal impacts on genetic diversity remain poorly understood, hindering species conservation and management. Walnuts, generally referred to as Juglans regia and J. sigillata , are economically vital in Asia, but little is known about their genetic origins and how the species will be affected by future...
Androgen induces 3′UTR shortening of de novo lipogenesis genes by alternative polyadenylation in prostate cancer cellsNARA Subscribed
Alternative polyadenylation (APA) is a pervasive mechanism that is emerging as a formidable player in post-transcriptional regulation. The transcriptional landscape can be altered via APA in response to various stimulating factors. Using the PacBio single-molecule long-read sequencing method, we present for the first time the 3′UTR landscape and reveal a global increase of APA events in prostate cancer (PCa) LNCaP cells in res...