With around 2 billion cases each year, infectious gastroenteritis remains a worldwide health problem. A major cause of acute gastroenteritis is infection with enteric viruses, which often leads to hospitalization in children and immunocompromised people. We adapted and validated a gastrointestinal qPCR panel, which simultaneously detects the most common enteric viruses: Norovirus GI and GII, Rotavirus, Adenovirus, Sapovirus, A...

Background The abscopal effect (AbE) refers to the regression of non-irradiated tumors following localized radiotherapy (RT), suggesting a systemic immune-mediated response. The combination of RT with immunotherapy (IO) has been proposed to enhance the AbE by overcoming RT-induced immunosuppressive mechanisms, but robust evidence, specifically in non-small cell lung cancer (NSCLC), is lacking. This study aimed to determine the...

This study investigates the neural and behavioral mechanisms of tactile perceptual discrimination using fMRI and a set of wrinkled surface stimuli with varying textures. Fifteen female participants were tasked with distinguishing between different surfaces by touch alone. Behavioral results demonstrated variable discriminability across conditions, reflecting the tactile sensitivity of human fingertips. Neural analysis showed v...

This paper focuses on the critical role of integrative leadership in inter- and transdisciplinary (ITD) research programs. ITD programs have become one of academia’s responses to address contemporary sustainability challenges. Fulfilling the promise of such programs is extraordinarily challenging for all involved participants, but especially for program leaders who have to ensure that the perspectives of the involved program p...

Aims Soil organic carbon (SOC) stocks of croplands can be enhanced by targeted management, which boosts soil fertility and contributes to climate change mitigation. One SOC sequestration option is adopting cover crops. The aim of this study was to quantify the SOC sequestration potential of cover crops in Germany. Methods We simulated SOC scenarios on 1,267 cropland sites with site-specific management data using an SOC model e...

In July 2021 extreme rainfall across Western Europe caused severe flooding and substantial impacts, including over 200 fatalities and extensive infrastructure damage within Germany and the Benelux countries. After the event, a hydrological assessment and a probabilistic event attribution analysis of rainfall data were initiated and complemented by discussing the vulnerability and exposure context. The global mean surface tempe...

This study aims at the synthesis and initial biological evaluation of novel rhenium–tricarbonyl complexes of 3,3′,4′,5,7-pentahydroxyflavone (quercetin), 3,7,4΄-trihydroxyflavone (resokaempferol), 5,7-dihydroxyflavone (chrysin) and 4΄,5,7-trihydroxyflavonone (naringenin) as neuroprotective and anti-PrP agents. Resokaempferol was synthesized from 2,2΄,4-trihydroxychalcone by H 2 O 2 /NaOH. The rhenium–tricarbonyl complexes of t...

Although Atlantic cod has been observed in Svalbard waters since the 1880s, knowledge about the presence in the Arctic shallow water zone is limited. The regular catch of juvenile Atlantic cod in Kongsfjorden since 2008 is in line with an overall northward shift of boreal fish species toward the Arctic. This is the first study showing the age class composition, growth rates, and stomach content of Atlantic cod in the shallow w...

Baobab ( Adansonia digitata L.) is a multipurpose, drought resistant, wild fruit tree, endemic to arid and semi-arid lands of Sub-Saharan Africa. Baobab populations have been showing a lack of regeneration, and therefore causes concern for the species survival. This study investigated the state, distribution and use of baobabs in an under-researched population in Kenya, to identify the potential for further use and development...

Aim To examine the contribution of large‐diameter trees to biomass, stand structure, and species richness across forest biomes. Location Global. Time period Early 21st century. Major taxa studied Woody plants. Methods We examined the contribution of large trees to forest density, richness and biomass using a global network of 48 large (from 2 to 60 ha) forest plots representing 5,601,473 stems across 9,298 species and 210 plan...

Global change is impacting forests worldwide, threatening biodiversity and ecosystem services including climate regulation. Understanding how forests respond is critical to forest conservation and climate protection. This review describes an international network of 59 long‐term forest dynamics research sites ( CTFS ‐Forest GEO ) useful for characterizing forest responses to global change. Within very large plots (median size...