M. A. Rashed results 48
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The gut-brain axis plays a vital role in migraine pathophysiology. Studies highlight reciprocal interactions between the central nervous system and the gastrointestinal tract. Previous research suggests that factors such as gut microbiota profiles, inflammatory mediators, neuropeptides, serotonin pathways, stress hormones, and nutritional substances influence this interaction. The pathophysiology of migraine has been linked to...
The blood–brain barrier (BBB) is a stringent barrier that restricts the successful brain delivery of polar neurotherapeutics molecules. One such molecule is Zonisamide (ZNS), a hydrophilic centrally acting anti-epileptic drug. This study aims to overcome the poor ZNS BBB permeability using the nose-to-brain (NTB) carbon-based biocompatible nanodiamonds (ND) delivery system to deliver ZNS directly to the brain, bypassing the BB...
Bisphenol A (BPA) is a widely used endocrine disruptor that represents a significant risk to male reproductive function. Zinc (Zn) is vital for appropriate development of testes and to guarantee optimal testicular function and spermatogenesis. Our goal was to investigate if zinc oxide (ZnO), either in conventional or nanoformulation, could safeguard adult male rats’ reproductive performance against the damaging effects of BPA....
The distinct and species-specific chemical compounds found on the insect cuticle have demonstrated effectiveness in various applications, including species identification. Accurate identification of fly species becomes challenging when only damaged empty puparial cases are available, making it difficult to use traditional morphological and molecular identification methods. This study aimed to analyze the chemical compositions...
Preparation and characterization of nanomuscovite by intercalation method for adsorption of heavy metals from polluted waterNARA Subscribed
In this study, nanomuscovite adsorbents were prepared by intercalation with various organic intercalates (DTAB-TTAB-DTPA-PA-PN) and used to remove Cd 2+ and Pb 2+ from polluted water. The best nanomuscovite was prepared using DTPA and muscovite (Muc/DTPA) and characterized by XRD, TEM, EDX, FTIR, and BET surface area. The developed nanoadsorbent was used to remove Cd 2+ and Pb 2+ from polluted water. The effect of various fact...
Characterization and phylogenetic analysis of the complete mitochondrial genome of Mango tilapia (Sarotherodon galilaeus: Cichlidae)NARA Subscribed
Background Sarotherodon galilaeus (Linné, 1758) is a member of the family Cichlidae, which is considered the most important aquaculture freshwater species endemic to Africa and the Middle East. The genetics and molecular biology of this species are rare. This requires more comprehensive mitochondrial genomes-based phylogenetics to enhance understanding of the relationship and delineate this species. Methods and results Here, w...
Breast cancer is one of the most prevalent and deadliest cancers among women in the world because of its aggressive behavior and inadequate response to conventional therapies. Mesenchymal stem cells (MSCs) combined with green nanomaterials could be an efficient tool in cell cancer therapy. This study examined the curative effects of bone marrow–derived mesenchymal stem cells (BM-MSCs) with selenium nanoparticles (SeNPs) coated...