The challenge of protecting marine ecosystems, including biodiversity and manifold interactions in changing environments, has encouraged development of end-to-end models linking physical drivers through entire food webs to upper-level predators. Ideally such models should have temporal and spatial resolution adequate to capture important small-scale processes, while including scales large enough to encompass local food webs an...

Germplasm banks are important for preserving genetic diversity, yet the availability and long-term maintenance of macroalgal strains in germplasm banks is currently limited in European collections. To support future food security, restoration efforts, and biotechnological innovation, a strategy was recently developed for the long-term preservation of macroalgal genetic diversity. A foundational step in this effort is to assess...

Mirtazapine is an atypical tetracyclic antidepressant drug that binds to several monoamine neurotransmitter receptors. For instance, mirtazapine binds to H 1 -histamine receptors in vitro and in the brain of patients in vivo. Here, we hypothesize that mirtazapine is an antagonist at human cardiac H 1 -histamine receptors. To test this hypothesis, we measured force of contraction in isolated electrically stimulated (1 Hz) left...

Areas along the US continental shelf that have been designated for extensive offshore wind farm installations over the coming decades overlap with regions that support economically important fisheries. These fisheries are undergoing changes in distribution in response to warming ocean water temperatures. The combination of expanding offshore wind energy infrastructure and changing environmental conditions presents new challeng...

The Atlantic surfclam, Spisula solidissima supports a lucrative commercial fishery in the Mid‐Atlantic Bight (MAB) worth roughly $30 million in revenue per year. Rapid climate change is expected to modify the geographic range of the Atlantic surfclam, with consequences for the surfclam fishery. This study evaluated fishery‐based indicators projected from 2020 through 2095 based on anticipated changes in the geographic range an...

Offshore wind energy development on the Mid‐Atlantic Bight (MAB) portion of the Northwestern Atlantic continental shelf could have adverse impacts on the future of the Atlantic surfclam, Spisula solidissima , fishery. The current and potential future areas designated for offshore wind energy development overlap with the present‐day and projected Atlantic surfclam fishing grounds and so could limit the fishery. Fishery impacts...

The Atlantic surfclam, Spisula solidissima , and ocean quahog, Arctica islandica , are biomass dominant bivalve species on the eastern North American continental shelf, both supporting lucrative commercial fisheries in the Mid‐Atlantic with a combined value of about $53.6 million in ex‐vessel revenue per year. The thermal tolerance of Atlantic surfclam is generally below 20 °C, whereas the boreal ocean quahog resides in colder...

Clozapine is an atypical antipsychotic (neuroleptic) drug. Clozapine binds to H 2 -histamine receptors in vitro. We wanted to test the hypothesis that clozapine might be a functional antagonist at human cardiac H 2 -histamine receptors. To that end, we studied isolated electrically stimulated left atrial preparations and spontaneously beating right atrial preparations from transgenic mice with cardiomyocyte-specific overexpres...

Ornamental aquaculture and fishkeeping are very popular with millions of enthusiasts worldwide. The number of newly imported fish species for ornamental purposes grew slowly from World War I until the 1980s. It then exponentially increased until now with more than 7900 species and a large number of scientifically undescribed morphotypes. Here we present the first comprehensive review of freshwater and brackish fish importation...