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Hereditary gynecological cancer management in women with Lynch syndrome: a survey across EuropeNARA Subscribed
We aim to compare clinical practices in the gynecological management of women with Lynch syndrome across Europe and assess the need for multidisciplinary gynecological care for this high-risk population. European gynecologists involved in the clinical care of women with Lynch syndrome were invited to complete a cross-sectional survey regarding their clinical practices and organization of care. All participating gynecologists w...
Metabolic Regulation in the Induction of Trained ImmunityNARA Subscribed
The innate immune system exhibits features of memory, termed trained immunity, which promote faster and more robust responsiveness to heterologous challenges. Innate immune memory is sustained through epigenetic modifications, affecting gene accessibility, and promoting a tailored gene transcription for an enhanced immune response. Alterations in the epigenetic landscape are intertwined with metabolic rewiring. Here, we review...
Land‐use intensification reduces functional redundancy and response diversity in plant communitiesNARA Subscribed
Ecosystem resilience depends on functional redundancy (the number of species contributing similarly to an ecosystem function) and response diversity (how functionally similar species respond differently to disturbance). Here, we explore how land‐use change impacts these attributes in plant communities, using data from 18 land‐use intensity gradients that represent five biomes and > 2800 species. We identify functional groups u...
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