Nature contributes to our quality of life through a wide range of non-material Nature’s Contributions to People (NCP), including aesthetic enjoyment, restorative experiences and recreational opportunities. However, quantifying and managing the supply of non-material NCP requires a mechanistic understanding of how they are associated with the entities of nature that support them across different ecological contexts. We characte...

Summary Mesenchymal stromal cells (MSCs) ameliorate pre-clinical sepsis and sepsis-associated acute kidney injury (SA-AKI) but clinical trials of single-dose MSCs have not indicated robust efficacy. This study investigated immunomodulatory effects of a novel MSC product (CD362-selected human umbilical cord-derived MSCs [hUC-MSCs]) in mouse endotoxemia and polymicrobial sepsis models. Initially, mice received intra-peritoneal (...