The genus Streptomyces is recognized as a source of secondary metabolites (SMs) with applications in medicine, industry, and agriculture. This study presents the description and characterization of a new Streptomyces species, isolated from sediments of the Madeira River in the Brazilian Amazon. Four strains (CPAA MAD 27, CPAA MAD 39, CPAA MAD 42, and CPAA MAD 51) were obtained from sampling sites distributed along the river. T...

The increasing resistance of Pseudomonas aeruginosa to carbapenem antibiotics is shifting the landscape of high-risk clones from a strictly hospital-acquired threat to a global pathogen with One Health relevance. Given the limited therapeutic options available, developing new treatments is essential. We previously reported the complete genome sequence of φSPM-1 phage from the family Myoviridae . In this study, we show that φSP...

Aim We evaluated how native vegetation cover influences the diversity of arachnid assemblages across multiple spatial scales in major Brazilian ecosystems. Location Brazil (Amazon and Atlantic rainforests, Cerrado savanna and Caatinga dry forest). Taxon Arachnida (Opiliones, Pseudoscorpiones and Scorpiones). Methods We sampled arachnids at 120 sites using active search and litter sifting. Native vegetation cover was quantified...

Historically Amblyomma hebraeum has been found in the north-eastern part of South Africa and along the coastal belt stretching to the Eastern Cape area. A change already noted in the past 20 years has been the increase in distribution area in the Eastern Cape, which now includes a larger inland area. It has been postulated that climate change has brought about a change in the distribution of A. hebraeum and subsequently, its p...

The use of germling clusters derived from spontaneous sporulation offers a promising strategy to stabilize Ulva cultivation, particularly during reproductive events that compromise biomass yield. This study assessed the growth, photophysiological responses, and biochemical composition of unattached Ulva sp. germling clusters cultivated in flat-bag photobioreactors under two different nutrient supplement rates: nitrate addition...

Purpose The European Medicines Agency (EMA) guideline Declaration of Storage Conditions in the Product Information of Medicinal Products (CPMP/QWP/609/96/Rev.2) was last revised in 2007. Since then, advances in stability science, increased climatic variability, and evolving regulatory expectations have highlighted limitations in the framework, particularly the use of vague descriptors such as “room temperature” or “no special...

Rock outcrops are geological formations that harbor a highly specialized biota adapted to harsh environmental conditions that differ from their surrounding landscapes. They are globally distributed, especially in old, highly weathered landscapes, and can function as habitat islands containing high levels of endemism and distinct evolutionary lineages. Despite their ecoevolutionary importance, rock outcrops remain largely overl...

WHO ranked chronic inflammatory diseases as the most significant cause of death. The current therapeutic approach is the constant administration of clinically available anti-inflammatory drugs; however, this strategy presents severe side effects. New entities derived from plants have shown their potential for developing safe and effective therapies. Particularly, Echinacea purpurea extracts have demonstrated strong anti-inflam...

Volcanic eruptions represent significant episodic sources of atmospheric pollutants, emitting large amounts of particulate matter (PM), sulfur dioxide, and trace metals. These emissions are associated with adverse cardiovascular and respiratory health outcomes, yet the specific chemical constituents responsible remain insufficiently defined. This study investigates the chemical composition and biological effects of water-solub...

Leaf herbivory is a ubiquitous ecological interaction that varies significantly in intensity across species, habitats, and biogeographic regions. Although quantification of leaf damage is crucial for understanding many ecological processes, the accuracy and precision of various damage estimation methods used by researchers, including visual estimation, digital image analysis, and artificial intelligence, have not been evaluate...