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Cervicothoracic trans-spinal magnetic stimulation: effect of coil position and orientation on spinal motor evoked potentialsNARA Subscribed
Stroke is a leading cause of long-term adult disability, and over 80% of survivors have persistent upper limb motor impairment. Spinal electrical stimulation has shown therapeutic potential after neurological disorders. Post-stroke applications have largely relied on invasive implants that limit clinical adoption, and non-invasive high intensity electrical stimulation may be intolerable for those with residual sensory function...
Population size estimation is critical for determining sustainable harvest levels of hunted species. Spatial capture-recapture via non-invasive genetic sampling is one method employed to estimate population size and is especially useful in habitats where aerial surveys are not possible. Developments in DNA sequencing technologies have led to the application of amplicon-based genotyping-in-thousands by sequencing (GTseq) for ge...
Interpretable deep learning reveals spatiotemporal MRI features of brain aging that align with neurodegenerationNARA Subscribed
Cortical thinning and atrophy are hallmarks of brain aging that have been characterized using magnetic resonance imaging (MRI). Brain aging involves many neuroanatomic features whose effects on brain structure remain unexplored. To address this challenge, we trained interpretable deep neural networks (DNNs) to estimate brain age (BA) from T 1 -weighted ( T 1 w) MRI. By identifying MRI features unapparent to humans, DNNs can fi...
Evaluating MPA success for Caribbean reef fish: the role of design, habitat, and managementNARA Subscribed
Marine protected areas (MPAs) are essential tools for protecting marine ecosystems; yet, their effectiveness varies across regions. In the Caribbean, home to some of the world’s most degraded reefs, evaluating MPA performance requires consistent ecological data and information on management practices. To address this, we conducted standardised reef fish surveys of small (< 20 cm) and large (≥ 20 cm) fish across 83 sites in ten...
Diversity and Potential Endemism of New Zealand Freshwater Rotifers Revealed Using Mitochondrial DNA BarcodesNARA Subscribed
Rotifers perform key functions in aquatic food webs and respond to environmental changes, thus providing sensitive indicators of water quality. However, rotifers are small, highly diverse, and difficult to identify for those lacking expertise. Monogononta are the largest taxonomic class of rotifers with over 1500 species described globally, and around 355 known from New Zealand; only four of these are currently recognised as e...
Alzheimer’s disease (AD) disproportionately affects women and carriers of the apolipoprotein E ε4 allele (APOE4), yet little is known about how sex and APOE interact to influence white matter (WM) integrity during disease progression. We integrated diffusion MRI and matched blood transcriptomic data to investigate these interactions and their underlying biological mechanisms. WM microstructure was quantified using diffusion te...
Objectives Physical activity is associated with reduced risk of prostate cancer (PCa) progression and death; changes in insulin sensitivity and inflammation are potential mediating mechanisms. This study examined whether exercise after PCa diagnosis affects insulin-related and inflammatory biomarkers. Methods The Active Surveillance Exercise (ASX) randomized controlled trial was assigned to men undergoing active surveillance f...
The Toxicology Investigators Consortium 2024 Annual ReportNARA Subscribed
The recovery of many cetacean species coincides spatially and temporally with intensifying anthropogenic threats. We undertook multi‐year systematic surveys to quantify seasonal abundance and document the distribution of at‐risk cetaceans, which is needed to assess the impacts of increasing human activities in the Canadian portions of the southern Salish Sea and Swiftsure Bank. We completed 21 line‐transect surveys encompassin...
Oncology Workforce: More than Meets the EyeNARA Subscribed
The current oncology workforce is struggling to keep up with demands for care. To address this shortage at The University of Kansas Cancer Center, we are educating the next generation about the breadth of careers at cancer centers. We describe the impetus for and process of developing an engaging infographic, “Charting the Course: Careers Along the Cancer Journey,” designed to resonate with high school students but which has a...
Global Review of Blue Carbon Ecosystem Microbial CommunitiesNARA Subscribed
Microbial communities underpin biogeochemical processes in Blue Carbon Ecosystems (BCEs); however, a comprehensive review of geographic patterns in microbial diversity, microbial functions, and distribution is currently lacking. Here, for the first time, we have analysed 70 years (1930–2020) of archaeal, bacterial, and fungal diversity and functions in mangrove, saltmarsh, and seagrass ecosystems to elucidate publication and g...