Iron is an essential micronutrient for brain development, participating in mitochondrial respiration, myelination, and neurotransmitter synthesis. However, previous studies have demonstrated that excessive iron during early postnatal life induces oxidative reactions, leading to mitochondrial dysfunction and synaptic failure. These alterations compromise energy metabolism and neuronal integrity, contributing to long-lasting cog...

Climate change is already altering, and will continue to reshape, the persistence and spatial structure of marine populations. Understanding metapopulation connectivity and local adaptation is therefore critical for identifying both vulnerable populations and those with adaptive resilience. We applied a seascape genomics approach to investigate connectivity patterns and adaptive responses in the honeycomb worm, Sabellaria alve...

The seasonality of forage production is one of the main challenges in semi-arid regions, where environmental conditions limit agricultural productivity. One promising option is the use of elephant grass ‘BRS Capiaçu’, together with deficit irrigation. This study evaluated the impact of different irrigation depths with brackish water (50%, 75%, 100% and 125% of the reference evapotranspiration – ET 0 ) on the productive, physio...

Aim We evaluated how native vegetation cover influences the diversity of arachnid assemblages across multiple spatial scales in major Brazilian ecosystems. Location Brazil (Amazon and Atlantic rainforests, Cerrado savanna and Caatinga dry forest). Taxon Arachnida (Opiliones, Pseudoscorpiones and Scorpiones). Methods We sampled arachnids at 120 sites using active search and litter sifting. Native vegetation cover was quantified...

Aim We investigate the distribution of dispersal modes — endozoochory (via animal ingestion), synzoochory (via animal seed accumulation) and anemochory (via wind)—and seed mass of woody plants across Brazilian ecosystems, testing whether their relative abundance in local plant communities could be predicted by climate, edaphic factors and dispersal agents (e.g., the main vectors moving seeds). We expected climate to be the mai...

Quaternary tufa carbonates from Brazil’s Potiguar Basin provide unique insights into the interplay of biogenic, hydrological, and climatic factors driving continental carbonate precipitation in tropical low-energy environments. This study systematically characterizes the depositional, taphonomic, and diagenetic features of the tufa deposits resulting from the dissolution of rocks from the Formação Jandaíra that overlie the lit...

L-DOPA (LD) is the gold-standard treatment of motor symptoms in Parkinson’s disease (PD), conventionally used to prove the predictive value of PD animal models. This study aimed to investigate the predictive validity of an adaptation of the conventional reserpine model of PD: the repeated low-dose reserpine administration in rodents, which promotes progressive motor impairment in catalepsy, vacuous chewing behavior tests, and...

The thrips, Scirtothrips dorsalis Hood (Thysanoptera: Thripidae), is native to Asia. Although it is still listed as a quarantine pest in Brazil, it has also been reported in this country. In the present study, we expanded the distribution of this species to southeastern Brazil and provided new records for the northeastern region, where it was initially detected. In addition, we warn about its expansion in the country, comment...

Myeloperoxidase (MPO) has been associated with a broad range of chronic inflammatory diseases since activated MPO catalyzes the production of HOCl, triggering both oxidative stress and inflammation. Since benzohydrazides are known as MPO inhibitors, a series of six N '-phenylbenzohydrazides and one quinazolin-4(3 H )-one analogue was evaluated through in vitro assays to measure inhibition of MPO, superoxide dismutase (SOD), an...