Background Neuroinflammation involves the activation of glial cells, particularly astrocytes, and microglia, in response to pathological stimuli. Astrocyte activation is characterized by increased pro-inflammatory cytokines and oxidative stress. Given their role in neuroinflammation, targeting astrocytic mechanisms presents potential therapeutic opportunities. Ellagic acid (EA), a phenolic compound, exhibits antioxidant, anti-...

Objectives To evaluate the microbiological quality of a hospital's treated water distribution system, characterize opportunistic bacterial isolates and their antimicrobial susceptibility profiles, investigate the genetic relatedness between environmental and clinical isolates from a One Health perspective. Study design Prospective observational study. Methods A total of 352 water samples were collected over six months from str...

The presence of Listeria monocytogenes in food represents a major challenge to food safety, especially in ready-to-eat products stored under refrigeration. This risk is associated with the ability of the pathogen to survive and multiply during prolonged refrigerated storage, making these foods potential sources of infection and a relevant public health concern. In this context, the aim of this study was to investigate the pres...