Tamandua mexicana is a mammal belonging to Xenarthrans, with high interest in medicine, conservation, and evolutionary studies. It has semiarboreal locomotion with specific adaptations to allow its movement on different substrates. To carry out this type of locomotion, the extrinsic muscles that allow scapular stabilization as well as retraction and protraction movements are essential. Despite their importance, no studies have...

As global temperatures rise, the life-history traits of many marine species are changing, with important implications for fish stocks, ecosystems, and fisheries. In fish populations, both plastic and genetic adaptations in traits like body size and maturity timing are influenced by fishing pressures and environmental changes. As ectothermic animals, fish rely on external temperatures to regulate physiological processes, making...

The aryl hydrocarbon receptor (AhR) is a ligand-activated transcription factor involved in xenobiotic sensing and multiple physiological functions, including intestinal homeostasis. Aging is associated with reduced colonic motility and constipation, but the contribution of AhR to intestinal motor function across sex and age remains incompletely defined. We performed a phenotypic characterization of AhR-deficient (AhR −/− ) and...

Excessive dietary fat intake is a major health concern, contributing to the increasing prevalence of Metabolic Dysfunction Associated with Fatty Liver Disease (MAFLD) worldwide; different prevalence between sexes has been postulated but it is not clear. This study evaluated the effects of a high-fat diet (HFD) in Wistar rats and the impact of a transition to standard or antioxidant-rich diets in the same animals, exploring dif...

Glypican-4 (GPC-4), an endothelial cell surface protein, is released into the circulation in the context of ischemia, inflammation, neurohumoral activity, and shear stress. This study aimed to investigate the prognostic value of GPC-4 in chronic heart failure. GPC-4 concentrations were determined in two prospective cohorts: patients with chronic heart failure with reduced ejection fraction (HFrEF), and with transthyretin amylo...

The emergence of Senecavirus A (SVA) as a causative agent of vesicular diseases in pigs is noteworthy, since it was identified in 2014 through outbreaks in Brazil. The SVA belongs to the Picornaviridae family and is a non-enveloped virus with the ability to adapt to the environment. As the virus’s stability allows it to persist on farms post-outbreak, maintaining stringent biosecurity measures is crucial for effective control....

Keymessage Standardized microhaplotype databases for eight diverse crops enable multiallelic analyses, comparative genetics, and breeding decisions. Abstract Microhaplotypes are short genomic segments that contain multiple tightly linked variants, providing multi-allelic data that can enhance genetic resolution compared to traditional biallelic single nucleotide polymorphism (SNP) markers. Here, we present the creation and uti...