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Flies from meat processing facilities are carriers of multidrug-resistant Escherichia coli and diverse Staphylococcaceae speciesNARA Subscribed
Flies are important vectors of antimicrobial resistance (AMR) in food production, but their role in meat processing environments remains poorly characterized. This study isolated Enterobacteriaceae and Staphylococcaceae (including Mammaliicoccus sciuri ) from flies collected in bovine and swine slaughterhouses and meat processing industries. Phenotypic AMR was assessed, and the presence of selected antimicrobial resistance and...
Macrophage modulation accounts for the anti-inflammatory effect of Hypnea cervicornis agglutinin in rat arthritis induced by zymosanNARA Subscribed
Previous study demonstrated that Hypnea cervicornis lectin (HCA) reduces inflammation and nociception via interaction with the lectin carbohydrate-binding site, modulating gene expression of the interleukins IL-1β, TNF-α and of iNOS. This study evaluated the effect of HCA in the rat model of arthritis induced by zymosan in the tibiotarsal joint and the involvement of macrophage-derived mediators. In vitro, macrophages were sti...
Associations of host gene expression in the brain, liver, muscle with fecal and cecal microbiota composition in pigsNARA Subscribed
Understanding the genetic regulation underlying host–microbiota interactions is key to elucidating how microbial communities influence host metabolism, immunity, and physiology. In this context, the main objective of this study was to integrate genomic, transcriptomic, and microbial data to identify shared regulatory variants, highlight key microbial taxa, and prioritize biological pathways related to lipid metabolism, immune...
Bokermannohyla frogs comprise species distributed across different Brazilian biomes, several of which are currently listed as endangered species. These anurans host a diversity of parasites that may negatively affect their survival. Several tick species of the family Argasidae and chigger mites of the family Leeuwenhoekiidae exhibit host specificity toward this group. Here, we report a case of co-parasitism by argasid ticks an...
A mechanistic approach about oxidative, mutagenic, and cytotoxic effects of an organotelluraneNARA Subscribed
Organotellurium (OTe) compounds have pharmacological properties, including leishmanicidal, antimalarial, and antifungal activities. Herein, we assessed cytotoxicity effects of OTe RF07 in a panel of tumor cell lines, as well as its oxidative, toxicity, and hemolytic actions. The toxicity was evaluated on Allium cepa and Artemia salina larvae. Cell viability was also assessed by resazurin in murine cells (Sarcoma 180), human ce...
Global patterns of native aluminum-accumulating plants indicate a predominance in tropical regions and specific taxonomic groupsNARA Subscribed
Background and aims Aluminium (Al) toxicity limits plant growth in acidic soils, affecting plant development and survival. However, some species are tolerant to Al, allowing them to grow under these conditions. In this study, we mapped the global distribution and main taxonomic groups of native Al-accumulating plants and analyzed spatial, temporal, and thematic patterns in the scientific literature on the subject. Methods We a...
HDV has a high genetic diversity among isolates and a high capacity to accumulate mutations over time. The mechanisms involved in the clinical progression of HDV are not fully elucidated. Few studies relate mutations to clinical implications, which makes this variable extremely relevant for research into HDV-3, a genotype associated with worse clinical progression. The aim of this study was to analyze mutations in complete gen...