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Physiological determinants and energy system contribution in short- and middle-distance cycling performanceNARA Subscribed
Purpose The purpose of this study was to investigate the contribution of aerobic and anaerobic energy release on cycling performance in 10 to 180 s. Methods 18 male cyclists from recreational- to elite level participated in this cross-sectional study. The cyclists were tested in oxygen cost of cycling (C), peak oxygen uptake (VO 2peak ), maximal sprint power (MSP), and five short time trials (TT): 10 s (10TT), 30 s (30TT), 60...
The Abrupt and Persistent Decline in Recruitment Success in Northeast Arctic Cod: A Review of Probable CausesNARA Subscribed
Most of the previously large cod stocks in the North Atlantic are depleted to very low levels. A notable exception has been the Northeast Arctic cod inhabiting the Barents Sea. This cod stock reached a record high level around 2013, but since then has declined sharply, with older fish being fished out and few new recruits entering the stock. More specifically, since 2006 the average recruitment at age 3 per unit spawning stock...
Comparative analysis of clinically approved lipid nanoparticles for intranasal siRNA delivery against SARS-CoV-2NARA Subscribed
SARS-CoV-2 continues to circulate globally, with persistent hospitalizations, despite a successful global vaccination strategy. We have developed highly conserved, antiviral short interfering (si)RNA and demonstrated in vivo antiviral efficacy following intranasal treatment of mice with naked siRNA. To enhance antiviral efficacy and siRNA protection, in this study we investigated the use of LNP packaging to improve delivery an...
Diagnostic performance of circulating microRNA signatures for differentiating tuberculosis disease from tuberculosis infectionNARA Subscribed
As regulators of innate and adaptive immunity, microRNAs (miRNAs) could aid in the discrimination between tuberculosis disease (TB) and (latent) TB infection (TBI). We analysed 754 circulating miRNAs in participants diagnosed with TB and TBI using TaqMan™ Advanced miRNA Human A and B cards. MiRNAs were normalized exogenously and endogenously via geometric means of selected reference miRNAs. Expression analysis was used to iden...
Determining physiologic variables for changes in 800-m running and 800-m ski ergometer performanceNARA Subscribed
Purpose This study investigates associations between changes in 800 m time trial performance in running or ski ergometer double poling, and changes in physiologic variables after a seven-week observational period. Forty six athletes ranging from recreational to elite level, participated in either a run (RUN) or a ski ergometer (SKI) observational study. Methods The participants performed pre- and post-tests in; 800-m time tria...
Background We aimed to describe the genomic epidemiology of vancomycin-resistant Enterococcus faecium (VREfm) in Eastern Denmark from 2020 to 2022, identify and characterise the vanB Transposon 1549 (Tn 1549 ) insertion sites among vanB VREfm clones and identify emerging VREfm clones. Methods We analysed all VREfm from our routine diagnostic sequencing during the study period. Using the Seqsphere + v.8.2.0 software (Ridom GmbH...
Maximal aerobic and anaerobic power and time performance in 800 m double poling ergometerNARA Subscribed
The purpose of this study was to investigate to what extent aerobic power (MAP), maximal anaerobic power (MANP), anaerobic capacity measured as time to exhaustion at 130% MAP (TTE), and maximal accumulated oxygen deficit (MAOD) correlated with 800 m double poling time trial performance (800TT) in a ski ergometer. A second aim was to investigate the relationship between TTE and MAOD, and to what extent TTE and MAOD would relate...
Meeting Paris agreement objectives will temper seabird winter distribution shifts in the North Atlantic OceanNARA Subscribed
We explored the implications of reaching the Paris Agreement Objective of limiting global warming to Alle alle , Fratercula arctica , Uria aalge , Uria lomvia and Rissa tridactyla ) using tracking data for ~1500 individuals through resource selection functions based on mechanistic modeling of seabird energy requirements, and a dynamic bioclimate envelope model of seabird prey. Future winter distributions were predicted to shif...
TRY plant trait database – enhanced coverage and open accessNARA Subscribed
Plant traits—the morphological, anatomical, physiological, biochemical and phenological characteristics of plants—determine how plants respond to environmental factors, affect other trophic levels, and influence ecosystem properties and their benefits and detriments to people. Plant trait data thus represent the basis for a vast area of research spanning from evolutionary biology, community and functional ecology, to biodivers...
ErratumNARA Subscribed
Two adjacent inversions maintain genomic differentiation between migratory and stationary ecotypes of Atlantic codNARA Subscribed
Atlantic cod is composed of multiple migratory and stationary populations widely distributed in the North Atlantic Ocean. The Northeast Arctic cod (NEAC) population in the Barents Sea undertakes annual spawning migrations to the northern Norwegian coast. Although spawning occurs sympatrically with the stationary Norwegian coastal cod (NCC), phenotypic and genetic differences between NEAC and NCC are maintained. In this study,...
Genome-wide association study of glioma and meta-analysisNARA Subscribed
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