Myasthenia gravis (MG) is a chronic autoimmune disorder that involves the targeting of neuromuscular junctions and is primarily driven by autoantibodies against the acetylcholine receptor (AChR). While genetic susceptibility is a factor, environmental triggers, particularly viral infections, are being increasingly investigated as potential contributors to MG pathogenesis. This review examines the complex interplay between vira...

Immune checkpoint inhibitor (ICI)–based combinations represent the standard first-line treatment for metastatic clear cell renal cell carcinoma (mRCC), although robust biomarkers for treatment selection remain undefined. We conducted a systematic review to identify biomarkers assessed in randomized clinical trials (RCTs) on first-line ICI-based regimens. Following PRISMA guidelines, we searched PubMed, Web of Science and Scopu...

In the context of tunnel excavation with Tunnel Boring Machines (TBM), the possibility of quickly determining, on site and with low-cost tools, both the grain size curve and the volume of the excavated muck, can support the correct setting of the machine and the possible reuse of the material itself for applications such as structural concrete for tunnel linings, road embankments and fillings and so on. For this purpose, uncon...

Introduction Human dirofilariasis, an emerging mosquito-borne zoonosis, is increasing, particularly in Europe. While subcutaneous presentations are the most common infections, genital presentations are rare and can pose significant diagnostic challenges. Purpose This review aims to provide an updated synthesis of all detailed published cases of genital dirofilariasis analyzing clinical characteristics, diagnostic methods, trea...

The aim of the present work was to investigate the influence of fasting and refeeding on body condition, gut physiology and microbiota in reared O. mykiss . Ninety-six fish were randomly allotted among three groups subjected to different feeding plan: C (control, fed for 5 weeks); R (restricted ration over 3 weeks followed by 2 weeks feeding); F (fasted over 3 weeks followed by 2 weeks feeding) in a well’s fresh water flow-thr...

Microalgae have been used as live food in aquatic species. In recent years, the interest in microalgae has considerably increased, thanks to the evolution of production techniques that have identified them as an ecologically attractive aquafeed ingredient. The present study provides the first data about the effects of dietary inclusion of a microalgae consortium grown in a high-rate algal pond system on zootechnical performanc...

Invasive alien species (IAS) are one of the greatest causes of native species extinction. Indeed, they represent a global threat for biodiversity and can also affect the economy and human health. The colonization success of IAS is presumably not only due to their biological and ecological characteristics, but also to the lack of predators and/or parasites in the invaded new areas. In the present work, we demonstrate evidence o...