Mark Ma results 91
· Newest (Page 1/4, per page 25)
Author: Mark Ma ×Clear All Filters
Search Results
Temporal transcriptomic profiling identifies core regulators in cytokine-induced gut barrier disruption in differentiated Caco-2 cellsNARA Subscribed
Objective The intestinal epithelial barrier maintains gut homeostasis, and its disruption contributes to inflammatory diseases such as Inflammatory Bowel Diseases (IBD). Although barrier restoration is a promising therapeutic strategy, most current approaches target immune responses rather than epithelial function. Since barrier injury and repair progress through discrete phases, this study aimed to define time-resolved epithe...
Organic ultraviolet filters in Irish sediments and biosolidsNARA Subscribed
Technical Considerations of Pharmacokinetic Assays for LNP-mRNA Drug Products by RT-qPCRNARA Subscribed
Lipid nanoparticle-messenger RNA (LNP-mRNA) drug products are a growing class of drug modalities. The unique composition of these drug products requires multiple measurements to account for the different components of these drug modalities. Pharmacokinetic (PK) measurements include measurement of the encapsulated mRNA and components of the LNP in circulation to understand the effectiveness of the therapeutic mRNA. The PK measu...
Hindcasted Body Temperatures Reveal Underestimated Thermal Stress Faced by Intertidal SpeciesNARA Subscribed
Aim As global climate changes, there is a clear mismatch between the temporal and spatial characteristics of body temperature and environmental temperature, confounding the assessment of thermal stress for organisms in many ecological studies. Here, we hindcast the hourly body temperatures of intertidal molluscs to explore the differences between them and environmental temperatures (air and water temperatures) in multiple metr...