Mathieu Gautier results 27
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Population Genomics of Incipient Allochronic Divergence in the Pine Processionary MothNARA Subscribed
Allochronic divergence is a key evolutionary mechanism that can frequently lead to incipient speciation. Although theoretical models suggest that such divergence is notably facilitated by small population size and genetic polymorphisms influencing reproductive timing, though constrained by genetic load, empirical validation remains limited. We investigated these predictions by re‐analysing a case of allochronic differentiation...
Global change is accelerating biological invasions, making it crucial to understand how species adapt in new environments to improve management strategies. Genomic data provide valuable insights into adaptation through genotype‐environment association (GEA) studies, which identify genes and biological processes tied to invasion success, and through geometric genomic offset (gGO) statistics, which estimate genetic (mal)adaptati...
The use of alternative methods to control cyst nematode populations has accelerated since the ban of chemical nematicides in Europe. The resistant QTL GpaV vrn , derived from the wild species Solanum vernei , is widely present in resistant European potato cultivars and provides strong protection against Globodera pallida populations although a risk of resistance breakdown has already been demonstrated in both experimental evol...
Temperature, rainfall and wind variables underlie environmental adaptation in natural populations of Drosophila melanogasterNARA Subscribed
While several studies in a diverse set of species have shed light on the genes underlying adaptation, our knowledge on the selective pressures that explain the observed patterns lags behind. Drosophila melanogaster is a valuable organism to study environmental adaptation because this species originated in Southern Africa and has recently expanded worldwide, and also because it has a functionally well‐annotated genome. In this...
Cadmium exposure enhances cell migration and invasion through modulated TRPM7 channel expressionNARA Subscribed
Cadmium is a xenobiotic involved in neoplastic transformation. Cadmium enters the cells through divalent cation transporters including the Transient Receptor Potential Melastatin-related 7 (TRPM7) which is known to be involved in cancer cell fate. This work aimed to study the role of TRPM7 in neoplastic transformation induced by cadmium exposure in non-cancer epithelial cells. Non-cancer epithelial cells were chronically expos...
Domestic species such as cattle ( Bos taurus taurus and B. t. indicus ) represent attractive biological models to characterize the genetic basis of short‐term evolutionary response to climate pressure induced by their post‐domestication history. Here, using newly generated dense SNP genotyping data, we assessed the structuring of genetic diversity of 21 autochtonous cattle breeds from the whole Mediterranean basin and performe...
Identifying genomic hotspots of differentiation and candidate genes involved in the adaptive divergence of pea aphid host racesNARA Subscribed
Identifying the genomic bases of adaptation to novel environments is a long‐term objective in evolutionary biology. Because genetic differentiation is expected to increase between locally adapted populations at the genes targeted by selection, scanning the genome for elevated levels of differentiation is a first step towards deciphering the genomic architecture underlying adaptive divergence. The pea aphid Acyrthosiphon pisum...
Adaptive admixture in the W est A frican bovine hybrid zone: insight from the B orgou populationNARA Subscribed
Understanding the adaptive response to environmental fluctuations represents a central issue in evolutionary biology. Population admixture between divergent ancestries has often been considered as an efficient short‐term adaptation strategy. Cattle populations from the West African Bos taurus × Bos indicus hybrid zone represent a valuable resource to characterize the effect of such adaptive admixture at the genome level. We he...
Estimation of population allele frequencies from next‐generation sequencing data: pool‐versus individual‐based genotypingNARA Subscribed
Molecular markers produced by next‐generation sequencing ( NGS ) technologies are revolutionizing genetic research. However, the costs of analysing large numbers of individual genomes remain prohibitive for most population genetics studies. Here, we present results based on mathematical derivations showing that, under many realistic experimental designs, NGS of DNA pools from diploid individuals allows to estimate the allele f...
The effect of RAD allele dropout on the estimation of genetic variation within and between populationsNARA Subscribed
Inexpensive short‐read sequencing technologies applied to reduced representation genomes is revolutionizing genetic research, especially population genetics analysis, by allowing the genotyping of massive numbers of single‐nucleotide polymorphisms ( SNP ) for large numbers of individuals and populations. Restriction site–associated DNA ( RAD ) sequencing is a recent technique based on the characterization of genomic regions fl...