Matthew Armstrong results 31
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The effect of intensity on metabolic and ventilatory responses to steady-state exercise in women across the adult lifecycleNARA Subscribed
Aim This study aimed to investigate the differences in metabolism and ventilation between women before, during, and after menopause during rest and to varying steady-state exercise intensities. Method 74 female participants (18–60 years; premenopausal [PRE], perimenopausal [PERI], and postmenopausal [POST]) completed four laboratory visits; one maximal exercise test, resting data collection, and body composition assessment fol...
Is individual heterogeneity in growth rates relevant to population dynamics of long‐lived reptiles?NARA Subscribed
Many populations show pronounced individual heterogeneity in traits such as somatic growth rates, but the relevance of this heterogeneity to population dynamics remains unclear. Individual heterogeneity may be particularly relevant to long‐lived organisms for which vital rates (survival and reproduction) increase with adult growth, as subtle differences in growth rates can have major fitness consequences. Previous analysis of...
Extensive regional variation in the phenology of insects and their response to temperature across N orth A mericaNARA Subscribed
Climate change models often assume similar responses to temperatures across the range of a species, but local adaptation or phenotypic plasticity can lead plants and animals to respond differently to temperature in different parts of their range. To date, there have been few tests of this assumption at the scale of continents, so it is unclear if this is a large‐scale problem. Here, we examined the assumption that insect taxa...
Comprehensive analysis of epigenetic clocks reveals associations between disproportionate biological ageing and hippocampal volumeNARA Subscribed
The concept of age acceleration, the difference between biological age and chronological age, is of growing interest, particularly with respect to age-related disorders, such as Alzheimer’s Disease (AD). Whilst studies have reported associations with AD risk and related phenotypes, there remains a lack of consensus on these associations. Here we aimed to comprehensively investigate the relationship between five recognised meas...
High‐resolution monitoring of water quality and ecosystem functioning over large spatial scales in expansive lowland river catchments is challenging. Therefore, we need modeling tools to predict these processes at locations where observations are absent. Here, we present a new approach to estimate ecosystem metabolism underpinned by a high‐resolution, process‐based model of in‐stream flows and water quality. The model overcome...
Contribution of warm habitat to cold‐water fisheriesNARA Subscribed
A central tenet of landscape ecology is that mobile species depend on complementary habitats, which are insufficient in isolation, but combine to support animals through the full annual cycle. However, incorporating the dynamic needs of mobile species into conservation strategies remains a challenge, particularly in the context of climate adaptation planning. For cold‐water fishes, it is widely assumed that maximum temperature...
Common, low-frequency, rare, and ultra-rare coding variants contribute to COVID-19 severityNARA Subscribed
The combined impact of common and rare exonic variants in COVID-19 host genetics is currently insufficiently understood. Here, common and rare variants from whole-exome sequencing data of about 4000 SARS-CoV-2-positive individuals were used to define an interpretable machine-learning model for predicting COVID-19 severity. First, variants were converted into separate sets of Boolean features, depending on the absence or the pr...
Resource waves: phenological diversity enhances foraging opportunities for mobile consumersNARA Subscribed
Time can be a limiting constraint for consumers, particularly when resource phenology mediates foraging opportunity. Though a large body of research has explored how resource phenology influences trophic interactions, this work has focused on the topics of trophic mismatch or predator swamping, which typically occur over short periods, at small spatial extents or coarse resolutions. In contrast many consumers integrate across...