Environmental stressors and sex‐specific life‐history strategies synergistically shape senescence patterns in ectotherms, yet their interactive effects on telomere dynamics remain poorly understood. This study investigates how altitude‐related environmental factors and sexual dimorphism drive telomere length variation in the montane salamander Pachytriton cheni across an elevational gradient (850–1350 m) in Qingliangfeng Natur...

The synthetase 3β-hydroxysterol-Δ24 reductase (DHCR24) is a key regulator involved in cholesterol synthesis and homeostasis. A growing body of evidence indicates that DHCR24 is downregulated in the brain of various models of Alzheimer’s disease (AD), such as astrocytes isolated from AD mice. For the past decades, astrocytic tau pathology has been found in AD patients, while the origin of phosphorylated tau in astrocytes remain...