The global consumption of antiviral drugs (AVD) during the ongoing pandemic has overwhelmed wastewater treatment plants, which struggle to effectively remove these compounds due to their hydrophilic nature. Current methods fall short of fully degrading AVDs, leaving behind potentially harmful residues. In this study, we aim to investigate the photocatalytic degradation of oseltamivir phosphate under UV light, with and without...

The fall aِrmyworm, Spodoptera frugiperda (J.E. Smith), causes significant yield losses due to its high fecundity, broad host range, defoliation capability, and voracious larval feeding. Biological control using microorganisms has gained attention as a sustainable alternative to chemical pest management. Entomopathogenic fungi employ distinct modes of action and produce secondary metabolites with insecticidal properties. This...

This study aimed to determine the prevalence, serovars, virulence gene profiles, antimicrobial resistance patterns, and extended-spectrum β-lactamase (ESBL) genes in Salmonella isolated from broiler chickens in Egypt. In this study, 200 samples were obtained from broiler chickens. Samples were processed using standard bacteriological techniques, and suspected isolates were biochemically identified and molecularly confirmed by...

Over the last decade, essential oils (EOs) have become potential ingredients for insecticide formulations due to their widespread availability and perceived safety. Therefore, this study aimed to evaluate the toxicity and biochemical efficacy of basil ( Ocimum basilicum ) (Lamiaceae) against two destructive pests Noctuidae, Agrotis ipsilon (Hufnagel) and Spodoptera littoralis (Boisduval) (Lepidoptera: Noctuidae). In addition,...

Neuroinflammation occurs in response to different injurious triggers to limit their hazardous effects. However, failure to stop this process can end in multiple neurological diseases. Doxycycline (DX) is a tetracycline, with potential antioxidant and anti-inflammatory properties. The current study tested the effects of free DX, DX-loaded calcium phosphate (DX@CaP), and pectin-coated DX@CaP (Pec/DX@CaP) nanoparticles on the lip...

Fasciola gigantica is one of the worldwide parasites that cause livestock and human illnesses. Chemotherapy is now the primary therapeutic option for its treatment. Drug abuse has led to the emergence of drug-resistant strains. As a result, there is an urgent need to discover natural and efficient anthelmintics against Fasciola spp. The study aims to evaluate the ovicidal activities of camel milk and its fractions on F. gigant...

Dysregulation of protein homeostasis, proteostasis, is a distinctive hallmark of many neurodegenerative disorders and aging. Deleteriously, the accumulation of aberrant proteins in Alzheimer’s disease (AD) is accompanied with a marked collapse in proteostasis network. The current study explored the potential therapeutic effect of vardenafil (VAR), a phosphodiesterase-5 inhibitor, in AlCl 3 / d -galactose ( d -gal)-induced AD i...