Frailty and cognitive impairments frequently co-occur in older adults. It remains unclear whether this overlap reflects shared underlying biological mechanisms or parallel but distinct disease pathways. We hypothesize that physical weakness and cognitive impairment share circulating markers already in an early disease stage. We therefore recruited and analyzed a relatively healthy population with partially overlapping pre-frai...

The Caatinga harbors the largest continuous expanse of Seasonally Dry Tropical Forests and Woodlands (SDTFW) in South America, characterized by a highly diverse flora and a significant number of endemic species. In this study, we compiled data on species distribution within the Caatinga by gathering information from 112 peer-reviewed floristic and phytosociological studies published up to December 2020. We characterized this d...

Rivers are recognised as providing valuable goods and services to society, and as hotspots of global biodiversity. Fish farming is an economically important activity associated with river systems; however, the effects of this industry on river health are not entirely understood. Studies evaluating interactions between freshwater fish farms and rivers are limited; therefore, we conducted a systematic review and an appraisal of...

An emerging new trend reveals that potent synthetic cannabinoid receptor agonists (SCRAs) that were prevalent prior to the Chinese class-wide ban in July 2021 have remained on the market or re-emerged. This is likely because of a new production route where unscheduled tail-less precursors are converted into the desired controlled SCRA via a one-step synthesis. This study reports the discovery of a clandestine production site i...