P. Walker results 326
· Newest (Page 1/14, per page 25)
Author: P. Walker ×Clear All Filters
Search Results
Community biocultural mapping reveals historical occupation and enables defense of African rainforestsNARA Subscribed
Global conservation maps often overlook community lands, impacting decision-making and reducing local agency. We focus on the high-profile and regionally important case of Massaha’s ancestral territory (Ibola Dja Bana Ba Massaha). In Gabon, the forest is largely gazetted into logging concessions and described as an Eden-like wilderness despite long-term human presence. We compare Massaha’s biocultural maps to global, colonial,...
Motivation The database initiated by the Mountain Invasion Research Network (MIREN) is one of the few globally implemented standardized vegetation surveys in mountains. The focus is on collecting plant species occurrences at 5‐year intervals along and adjacent to mountain roads spanning elevational gradients, with the goal of providing critical information about the ongoing spread of non‐native plants and the potential impacts...
Antimicrobial peptides (AMPs) are key components of the innate immune system in fish, providing rapid protection against microbial pathogens. Among these, the liver‐expressed antimicrobial peptides (LEAPs), comprising LEAP‐1 (hepcidin; HAMP) and LEAP‐2, play central roles in host defence and iron regulation. In this study, we present an integrated characterisation of the genomic organisation, tissue expression and dietary resp...
Diagnosing Linearity Along the Carbon Cascade in Terrestrial Biosphere Models and ObservationsNARA Subscribed
Elevated carbon dioxide (eCO 2 ) acts as a fertiliser for photosynthesis, driving an increase in gross primary production (GPP). However, it is unclear how effectively increased GPP propagates along the ‘carbon (C) cascade’ to increase net primary production (NPP) and vegetation C stocks ( C veg ) in different plant compartments. Vegetation models were criticised for being overly sensitive to photosynthesis (source‐driven), ne...
Under global climate change, co-occurrence of ocean acidification (OA) and warming poses a substantial threat to marine ecosystems. The present study focused on the Strait of Georgia within the Northeast Pacific region, where conditions of aragonite undersaturation exist year-round across the majority of the water column, with further intensification expected under OA. These conditions coincide with persistent rises in mean se...
A Review of a Decade of Anadromous Salmonid Hatchery (And Stocking) Research: Insights for Policy, Management and a Changing ClimateNARA Subscribed
Hatcheries and stocking programmes have long been a cornerstone of fisheries management, seen as tools for fisheries enhancement and/or conservation of threatened populations. Their use draws controversy, however, from a growing body of research over the last 50 years suggesting that stocking can have negative consequences for wild stocks, and yet remains valued in many contexts. This study systematically reviews a decade (201...
Interpretable deep learning reveals spatiotemporal MRI features of brain aging that align with neurodegenerationNARA Subscribed
Cortical thinning and atrophy are hallmarks of brain aging that have been characterized using magnetic resonance imaging (MRI). Brain aging involves many neuroanatomic features whose effects on brain structure remain unexplored. To address this challenge, we trained interpretable deep neural networks (DNNs) to estimate brain age (BA) from T 1 -weighted ( T 1 w) MRI. By identifying MRI features unapparent to humans, DNNs can fi...
Alzheimer’s disease (AD) disproportionately affects women and carriers of the apolipoprotein E ε4 allele (APOE4), yet little is known about how sex and APOE interact to influence white matter (WM) integrity during disease progression. We integrated diffusion MRI and matched blood transcriptomic data to investigate these interactions and their underlying biological mechanisms. WM microstructure was quantified using diffusion te...
The germline MLH1 c.-42 C > T (rs41285097) promoter variant has been identified in cases with MLH1-deficient colorectal or endometrial cancers but remains a variant of uncertain significance. Genetic testing identified two new MLH1 c.-42 C > T index cases from Australia and the USA. Clinicopathologic and molecular characterisation of tumour and non-neoplastic tissues was performed to investigate the potential mechanism of path...
With growing demand for land sector carbon abatement to support multiple objectives, there are calls to improve how social measures can be applied to inform investment decisions. Yet, limitations exist in using social measures to inform land-use investment and valuation frameworks. This study focuses on how social measures can inform the alignment of land sector investment priorities with regional social contexts. In partnersh...
Turnover in species composition often lags behind the pace of climate change, resulting in mismatches between climate and communities. However, the impact of these community‐climate disequilibria on ecosystem functions is rarely considered, and current methods for measuring disequilibria assume that species ranges were, until recently, in equilibrium with climate. Here, we develop a simple theoretical model to address both of...
Reticulospinal and corticospinal responses in long-term strength-trained and untrained adultsNARA Subscribed
Purpose Studies investigating neural adaptation to strength training have yet to determine the loci of previously observed improvements in motor pathway function. While transcranial magnetic stimulation (TMS) studies have typically focused on the corticospinal tract, recent evidence from primates suggests that the subcortical reticulospinal tract may be the primary candidate for adaptation. Methods: Using a cross-sectional com...