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A history of chronic adolescent stress attenuates cued fear-potentiated startle in adult female Wistar ratsNARA Subscribed
Rationale Post-traumatic stress disorder (PTSD) is a stress and trauma-related disorder that is largely characterized by hyperarousal to fear-based cues. N-methyl-D-aspartate (NMDA) receptors are key mediators of fear learning behaviors. Altered NMDA receptor signaling is a hallmark of PTSD pathology that impacts fear memory learning and extinction processes. Objectives In the current study, we tested whether exposing adolesce...
Addressing urgent conservation issues, such as the drastic declines of North American migratory birds, requires creative, evidence‐based, efficient, and collaborative approaches. The abundance of over 50% of monitored North American shorebird populations has declined by over 50% since 1980. To address these declines, we developed a partnership of scientists and practitioners called the Shorebird Science and Conservation Collec...
The use of plant genetic resources (PGR)—wild relatives, landraces, and isolated breeding gene pools—has had substantial impacts on wheat breeding for resistance to biotic and abiotic stresses, while increasing nutritional value, end‐use quality, and grain yield. In the Global South, post‐Green Revolution genetic yield gains are generally achieved with minimal additional inputs. As a result, production has increased, and milli...
Modeling genetic benefits and financial costs of integrating biobanking into the conservation breeding of managed marsupialsNARA Subscribed
Managed breeding programs are an important tool in marsupial conservation efforts but may be costly and have adverse genetic effects in unavoidably small captive colonies. Biobanking and assisted reproductive technologies (ARTs) could help overcome these challenges, but further demonstration of their potential is required to improve uptake. We used genetic and economic models to examine whether supplementing hypothetical capti...
Systems analysis of miRNA biomarkers to inform drug safetyNARA Subscribed
microRNAs (miRNAs or miRs) are short non-coding RNA molecules which have been shown to be dysregulated and released into the extracellular milieu as a result of many drug and non-drug-induced pathologies in different organ systems. Consequently, circulating miRs have been proposed as useful biomarkers of many disease states, including drug-induced tissue injury. miRs have shown potential to support or even replace the existing...
Beyond species counts for assessing, valuing, and conserving biodiversity: response to Wallach et al. 2019NARA Subscribed
Article impact statement : Combining native and non‐native species to evaluate biodiversity is overly simplistic and may undermine the conservation of ecosystems.
The ocean plays a crucial role in the functioning of the Earth System and in the provision of vital goods and services. The United Nations (UN) declared 2021–2030 as the UN Decade of Ocean Science for Sustainable Development. The Roadmap for the Ocean Decade aims to achieve six critical societal outcomes (SOs) by 2030, through the pursuit of four objectives (Os). It specifically recognizes the scarcity of biological data for d...
Variation in particulate C : N : P stoichiometry across the Lake Erie watershed from tributaries to its outflowNARA Subscribed
Human activities can cause large alterations in biogeochemical cycles of key nutrients such as carbon (C), nitrogen (N), and phosphorus (P). However, relatively little is known about how these changes alter the proportional fluxes of these elements across ecosystem boundaries from rivers to lakes. Here, we examined environmental factors influencing spatial and temporal variation in particulate C : N : P ratios across the Lake...
Constraints of philanthropy on determining the distribution of biodiversity conservation fundingNARA Subscribed
Caught between ongoing habitat destruction and funding shortfalls, conservation organizations are using systematic planning approaches to identify places that offer the highest biodiversity return per dollar invested. However, available tools do not account for the landscape of funding for conservation or quantify the constraints this landscape imposes on conservation outcomes. Using state‐level data on philanthropic giving to...