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Molecular characterization of extended-spectrum β-lactamases-producing Escherichia coli isolated from patients with bacteremiaNARA Subscribed
Bacteremia is a major health problem that affects millions of people worldwide. E. coli is one of the main pathogens associated with bacteremia and its resistance to the antimicrobial drugs, including β-lactams, has significantly increased in recent years. In view of the above, our objective was to determine the antimicrobial resistance profile of 60 E. coli isolates obtained from patients with bacteremia, as well as to charac...
Total plasma N-glycomic patterns of COVID-19 diseaseNARA Subscribed
Total plasma N -glycans alter in disease states, with few studies focused on COVID-19. A discovery cohort of 310 COVID-19 patients, replicated with 97 COVID-19 patients and tested with 100 COVID-19 patients, was used to unearth the N -glycans capable of distinguishing infection, as well as prognosis of intensive care unit (ICU) admission and mortality. All significant bisected glycans were decreased in patients compared to con...
Anaerobic metabolic responses of sludge and mine wastewater-derived consortia to winery wastewater-related compoundsNARA Subscribed
Winery wastewater contains readily biodegradable organic matter, but some of its components can inhibit anaerobic microbial activity. This study compares two enriched microbial consortia, derived from anaerobic digester sludge (ADS) and mining-process wastewater (MPW), exposed to alcohols, carboxylic acids, and phenolics. Assays were conducted in acetate–fumarate-based media containing low or high concentrations of each compou...
Cory’s Shearwater ( Calonectris borealis ), a migratory seabird from the Procellariidae family, is widely distributed across the Atlantic Ocean. It breeds on islands of Azores, Madeira, Canary, and Berlengas, and winters in coastal areas of South America and Africa. This species’ wide habitat range contributes to pathogen exchange across global regions. Plasmodium , a genus of apicomplexan parasites causing avian malaria, affe...
Objective To develop an endoscope reprocessing system using ozonated water jets. Methods The system features a jet head with concentric orifices that moves vertically to disinfect the external surface of the endoscope. Simultaneously, ozonated water is injected into the internal channel to ensure complete disinfection. Endoscopes were experimentally contaminated with Staphylococcus aureus and Escherichia coli . Quantitative an...
Submaximal walking increases MicroRNA-126 and angiogenic markers in men and women with peripheral arterial diseaseNARA Subscribed
Purpose Vascular dysfunction is a pathophysiological mechanism in peripheral artery disease (PAD). PAD patients exhibit reduced circulating expression of microRNA-126 (c-miRNA-126) and VEGF. Submaximal walking (SW) is recommended in PAD because it increases walking capacity, partially by improving vascular regulation, which can be observed after a walking session. Nevertheless, previous studies were conducted with maximal walk...
Aim We investigate the distribution of dispersal modes — endozoochory (via animal ingestion), synzoochory (via animal seed accumulation) and anemochory (via wind)—and seed mass of woody plants across Brazilian ecosystems, testing whether their relative abundance in local plant communities could be predicted by climate, edaphic factors and dispersal agents (e.g., the main vectors moving seeds). We expected climate to be the mai...
Subgroup-Specific Associations of GRIA Genes Encoding AMPA Glutamate Receptor Subunits with Patient Survival in MedulloblastomaNARA Subscribed
Brain cancers hijack biological systems involved in neural development and synaptic plasticity. Medulloblastoma (MB), the most common malignant brain tumor in children, is thought to arise from disruptions in neurodevelopmental programs. Glutamatergic transmission mediated by α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptors (AMPARs) has been implicated in synaptic communication between adult brain tumors a...
This study aimed to evaluate effects of replacing whole soybean grain with micronized defatted soybean meal (MDSM) in diets of lactating dairy cows on performance, digestion, metabolism, and milk yield and composition. Ten primiparous Jersey cows with an initial body weight (BW) of 410 ± 9 kg and 105 ± 5 days in milk were used. Five replacement levels (0, 25, 50, 75, and 100% of dietary DM) of whole soybean grain with MDSM wer...