R.F. Kelly results 117
· Newest (Page 1/5, per page 25)
Author: R.F. Kelly ×Clear All Filters
Search Results
Interpretable deep learning reveals spatiotemporal MRI features of brain aging that align with neurodegenerationNARA Subscribed
Cortical thinning and atrophy are hallmarks of brain aging that have been characterized using magnetic resonance imaging (MRI). Brain aging involves many neuroanatomic features whose effects on brain structure remain unexplored. To address this challenge, we trained interpretable deep neural networks (DNNs) to estimate brain age (BA) from T 1 -weighted ( T 1 w) MRI. By identifying MRI features unapparent to humans, DNNs can fi...
Local and Landscape‐Level Environmental Conditions Drive Habitat Selection Across Terrestrial Mammal SpeciesNARA Subscribed
Aim Animal movements are a fundamental process affecting communities and ecosystems. Quantifying habitat selection across species and habitats is key for understanding how animals respond to environmental change. Currently, we lack comparative studies that examine how habitat selection varies across species traits and landscapes. We aim to quantify global patterns of habitat selection to help understand the fundamental drivers...
Marine megafauna species are affected by a wide range of anthropogenic threats. To evaluate the risk of such threats, species’ vulnerability to each threat must first be determined. We build on the existing threats classification scheme and ranking system of the International Union for Conservation of Nature (IUCN) Red List of Threatened Species by assessing the vulnerability of 256 marine megafauna species to 23 at‐sea threat...
Protein kinase C iota (PKCι) and pVHL are both needed for lysosomal degradation of α5 integrin in renal carcinoma cellsNARA Subscribed
Background von Hippel-Lindau (VHL) hereditary cancer syndrome is caused by mutations in the VHL tumor suppressor gene and is characterized by a predisposition to form various types of tumors, including renal cell carcinomas, hemangioblastomas, and pheochromocytomas. The protein products of the VHL gene, pVHL, are part of an ubiquitin ligase complex that tags hypoxia inducible factor alpha (HIF-α) for proteosomal degradation. p...
The Atlantic Forest domain is a biodiversity hotspot with remarkable amphibian diversity, including over 700 species, 70% of which are endemic. Most of these endemic species have restricted geographic ranges, often confined to mountainous areas, as exemplified by the leptodactylid genus Crossodactylodes . These frogs are characterised by small body sizes, a bromeligenous habit and limited dispersal abilities, with species ofte...
Discovery of Genetically Distinct, Sympatric Coral Lineages With Temporal but Not Gametic Reproductive IsolationNARA Subscribed
Coral species abundance and biodiversity estimates are typically based on colony macromorphology. However, such measurements often underestimate the true diversity within coral communities because morphology does not necessarily reflect behavioral or genetic divergence. We previously reported on the unusual spawning behavior of the brain coral Diploria labyrinthiformis (Linnaeus, 1758) in Curaçao, Southern Caribbean, where thi...
Priorities, concerns, and potential compromises amongst urban forest stakeholders: international lessons from Aotearoa New ZealandNARA Subscribed
Urban forests provide numerous benefits including habitat for wildlife, improving human health, purifying air and water, and preventing and mitigating the effects of climate change. The need to protect and improve our urban forests will only increase as populations increase and cities densify and expand over time. However, urban forest establishment and maintenance is challenging due to a lack of effective policies, delays, la...
Aim Migratory birds are under threat by climate change. Successfully conserving them requires knowing which climatic factors drive changes in their migratory behaviour. Weather conditions may directly or indirectly affect the temporally disjointed life history stages of migratory birds, including the breeding, roosting and nonbreeding stages. However, the influences of these broad‐scale patterns are often not studied together....
Tropical ecosystems contain the world's largest biodiversity of vascular plants. Yet, our understanding of tropical functional diversity and its contribution to global diversity patterns is constrained by data availability. This discrepancy underscores an urgent need to bridge data gaps by incorporating comprehensive tropical root data into global datasets. Here, we provide a database of tropical root characteristics. This new...
Animals within social groups respond to costs and benefits of sociality by adjusting the proportion of time they spend in close proximity to other individuals in the group (cohesion). Variation in cohesion between individuals, in turn, shapes important group‐level processes such as subgroup formation and fission–fusion dynamics. Although critical to animal sociality, a comprehensive understanding of the factors influencing coh...