Emerging infectious diseases drive amphibian population declines worldwide. The chytrid fungus Batrachochytrium dendrobatidis ( Bd ) has caused severe losses, although impacts vary among species and environments. The Apennine yellow-bellied toad ( Bombina variegata pachypus ), endemic to Italy, has declined since the 1990s, yet Bd status in southern populations is poorly known. In 2024, we screened three populations within the...

Cervical cancer remains a major global health burden, particularly in low- and middle-income countries, necessitating the discovery of novel, accessible anticancer agents. Marine macroalgae, including Halymenia durvillaei , are rich in bioactive compounds with promising therapeutic potential. H. durvillaei collected from North Sulawesi, Indonesia, was extracted with methanol and fractionated into n-hexane, chloroform, ethyl ac...

Lewy body disease (LBD) and Alzheimer’s disease (AD) are the most common causes of cognitive decline and dementia and are associated with characteristic alterations in resting-state electroencephalographic (rsEEG) activity. This multicenter exploratory study investigated periodic and aperiodic rsEEG features in patients with cognitive decline due to Lewy body disease (LBCD) and Alzheimer’s disease (ADCD), compared with cogniti...

The flow convergence method includes calculation of the proximal isovelocity surface area (PISA) and is widely used to classify mitral regurgitation (MR) with echocardiography. It constitutes a primary decision factor for determination of treatment and should therefore be a robust quantification method. However, it is known for its tendency to underestimate MR and its dependence on user expertise. The present work systematical...