Cercospora leaf spot (CLS), caused by Cercospora beticola , is a severe threat to sugar beet ( Beta vulgaris ) production in Egypt’s Nile Delta and poses resistance and ecological problems to synthetic fungicides. This study investigates Alhagi maurorum (camelthorn), an endemic medicinal shrub of arid regions, and evaluates it as a sustainable plant-sourced biofungicide for integrated CLS management. Following molecular confir...

Sugar beet ( Beta vulgaris var. saccharum, L.), a primary contributor to the worldwide sugar market, suffers severely from powdery mildew caused by Erysiphe betae , which reduces the photosynthetic efficiency and therewith yields. This study presents molecular docking analysis and randomized complete block design (RCBD) field trials with nutrient foliar sprays to identify disease management strategies. The interaction study in...

Rheumatoid arthritis (RA) is an autoimmune disease primarily manifested by insistent proliferative synovitis, joint degradation, and bone erosions with no targeted therapy yet. Spirulina platensis serves as a treasure house of bioactive compounds with potential significance against different inflammatory ailments. Inspired by the potentiating biological attributes of S. platensis , the current investigation is concerned with d...

Implementing competent biosecurity strategies is a key factor for maintaining a disease-free aquaculture. Bacterial infections are an eminent threat to all live stages occurring in the marine hatchery. Live foods, including algae, rotifers, and artemia, are potential sources of microbial infections in hatcheries with ineffectual biosecurity plans. In the present study, epidemiological, bacteriological, molecular, and histopath...

Periodontitis is a prevalent inflammatory disease that leads to significant periodontal tissue destruction and compromised dental health, with its severity exacerbated in individuals with Diabetes Mellitus (DM). This review explores the complex relationship between mitochondrial dysfunction and periodontitis in diabetic patients. Recent studies indicate that the excessive production of reactive oxygen species (ROS), primarily...

Non-small cell lung cancer (NSCLC) is a widespread highly malignant type of lung cancer. Conventional chemotherapeutic drugs may be accompanied by both drug resistance and serious side effects in patients. Therefore, safer and more effective medications are urgently needed for the treatment of NSCLC. This study investigates the mode of action of 21 phytoconstituents previously isolated from the Amaryllidaceous plants Crinum bu...

Background MicroRNA and cell-free DNA have shown significant correlations with several autoimmune disorders including systemic lupus erythematosus (SLE). SLE has been associated with challenges in determining its activity, so that the need for biomarkers contributing to assessing its activity is emerging. The current study investigated miRNA-21, miRNA-146a and plasma cf-DNA in determination of SLE activity, in addition their a...