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NARA Subscribed2
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Springer Nature2
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GeroScience1
Inflammation Research1
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20241
20221
Ru Liu-Bryan results 2 · Newest (Page 1/1, per page 25)
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The NADase CD38 is a central regulator in gouty inflammation and a novel druggable therapeutic targetNARA Subscribed
Inflammation Research · 2024 · Vol. 73 · Issue 5 · Springer
Paulo Gil Alabarse; Patricia Oliveira; Huaping Qin; Tiffany Yan; Marie Migaud; Robert Terkeltaub; Ru Liu-Bryan
Objectives Cellular NAD + declines in inflammatory states associated with increased activity of the leukocyte-expressed NADase CD38. In this study, we tested the potential role of therapeutically targeting CD38 and NAD + in gout. Methods We studied cultured mouse wild type and CD38 knockout (KO) murine bone marrow derived macrophages (BMDMs) stimulated by monosodium urate (MSU) crystals and used the air pouch gouty inflammatio...
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A fly GWAS for purine metabolites identifies human FAM214 homolog medusa, which acts in a conserved manner to enhance hyperuricemia-driven pathologies by modulating purine metabolism and the inflammatory responseNARA Subscribed
GeroScience · 2022 · Vol. 44 · Issue 4 · Springer
Tyler A. U. Hilsabeck; Ru Liu-Bryan; Tracy Guo; Kenneth A. Wilson; Neelanjan Bose; Daniel Raftery; Jennifer N. Beck; Sven Lang; Kelly Jin; Christopher S. Nelson; Tal Oron; Marshall Stoller; Daniel Promislow; Rachel B. Brem; Robert Terkeltaub; Pankaj Kapahi
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