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Bridging Aquaculture and Human Medicine: A Comprehensive Review of Zebrafish Models for Chronic Kidney DiseaseNARA Subscribed
Chronic kidney disease (CKD) poses a significant global health burden, necessitating robust animal models for mechanistic studies and drug discovery. Zebrafish offers unique advantages as a powerful models in kidney disease, including high‐throughput compatibility, optical transparency, and significant genetic and nephron homology with both humans and farmed teleosts. However, challenges, such as the species' potent regenerati...
Under the current global biodiversity crisis, there is a need for automated and noninvasive monitoring techniques that can gather large amounts of data cost‐effectively at various ecological scales, from local to large spatial scales. These data can then be analyzed to inform stakeholders and decision‐makers. One such technique is passive acoustic monitoring, which is commonly coupled with automatic identification of animal sp...
The roles of non‐antibiotic pharmaceuticals in shaping the dissemination behaviours of antibiotic resistance genes (ARGs) in wastewater treatment systems remain poorly understood, and the influences of their transformation products have been overlooked. Here, we unveil more profound impacts of the metformin (MET) biotransformation product than the parent pollutant on the microbial community structure and ARG propagation of was...