S. Bouchard results 29
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Purpose Cancer incidence is rising among young adults (20–39 years), and it is one of the top five causes of death for this age group. Young adults often experience longer delays in diagnosis than children and older adults, which negatively impacts survival and quality of life. Communication interventions might help reduce these delays, but understanding the factors driving delays is crucial for developing effective strategies...
Freshwater biodiversity in a rapidly changing Arctic: An expert horizon scan of key research questionsNARA Subscribed
Arctic freshwater biodiversity is rapidly changing due to climate warming, resource extraction, infrastructure development, and landscape transformation. To improve understanding, predict future responses, and inform policy formulation, research needs must be clearly identified. Using a horizon scan survey, Arctic freshwater experts from government, international agencies, and Indigenous Peoples identified 77 biodiversity rese...
MicroBayesAge: a maximum likelihood approach to predict epigenetic age using microarray dataNARA Subscribed
Certain epigenetic modifications, such as the methylation of CpG sites, can serve as biomarkers for chronological age. Previously, we introduced the BayesAge frameworks for accurate age prediction through the use of locally weighted scatterplot smoothing (LOWESS) to capture the nonlinear relationship between methylation or gene expression and age, and maximum likelihood estimation (MLE) for bulk bisulfite and RNA sequencing da...
Aging is a complex biological process influenced by various factors, including genetic and environmental influences. In this study, we present BayesAge 2.0, an upgraded version of our maximum likelihood algorithm designed for predicting transcriptomic age (tAge) from RNA-seq data. Building on the original BayesAge framework, which was developed for epigenetic age prediction, BayesAge 2.0 integrates a Poisson distribution to mo...
The diel vertical migration (DVM) of zooplankton is one of the largest species migrations to occur globally and is a key driver of regional ecosystems and the marine carbon pump. Previously thought to be hampered by the extreme light regime prevailing in the Arctic Ocean, observations have revealed that DVM does occur in ice-covered Arctic waters and suggest the decline in Arctic sea ice may thereby impact DVM and its role in...
Aim To determine the relationships between the functional trait composition of forest communities and environmental gradients across scales and biomes and the role of species relative abundances in these relationships. Location Global. Time period Recent. Major taxa studied Trees. Methods We integrated species abundance records from worldwide forest inventories and associated functional traits (wood density, specific leaf area...
Coastal Polynya Disrupts the Acoustic Backscatter Diurnal Signal Over the Eastern Laptev Sea ShelfOA Marine
The diel vertical migration (DVM) of zooplankton is one of the largest species migrations to occur globally and is a key driver of regional ecosystems and the marine carbon pump. The dramatic changes in the Arctic environment in recent years, mainly associated with sea-ice decline, may have wide significance for the Arctic shelf ecosystems including DVM. Observations have revealed the occurrence of DVM in ice-covered Arctic wa...
Sensitivity assessment of sea lice to chemotherapeutants: Current bioassays and best practicesNARA Subscribed
Traditional bioassays are still necessary to test sensitivity of sea lice species to chemotherapeutants, but the methodology applied by the different scientists has varied over time in respect to that proposed in “Sea lice resistance to chemotherapeutants: A handbook in resistance management” (2006). These divergences motivated the organization of a workshop during the Sea Lice 2016 conference “Standardization of traditional b...
Enhanced detection of infectious salmon anaemia virus using a low‐speed centrifugation technique in three fish cell linesNARA Subscribed
Infectious salmon anaemia ( ISA ), caused by ISA virus ( ISAV ), is a serious disease of farmed A tlantic salmon, S almo salar L . Recently, molecular‐ and immunofluorescent‐based techniques have become powerful diagnostic tools for ISAV detection, but culture‐based techniques remain the gold standard. A disadvantage of ISAV culture is that the incubation time required before cytopathic effect ( CPE ) is observed in cell monol...
An assessment of nitrogen removal from headwater streams in an agricultural watershed, northeast Ohio, U.S.ANARA Subscribed
The objective of this project was to assess in‐stream nitrogen removal capacity in a fragmented agricultural landscape and to compare removal capacities in streams with agricultural or residential (hereafter referred to as agricultural streams) and forested riparian land use. We also identified what stream characteristics control nitrogen removal in these systems. We examined paired reaches (one agricultural and one forested r...
Estimating diagnostic test accuracy for infectious salmon anaemia virus in Maine, USANARA Subscribed
Infectious salmon anaemia virus (ISAV) is a pathogen of consequence to farmed Atlantic salmon, Salmo salar L. ISA control centres on active surveillance for early detection by reverse transcription polymerase chain reaction (RT‐PCR), indirect fluorescent antibody assay (IFAT) and virus isolation. Because diagnostic test performance varies among populations and laboratories, the Office International des Epizooties (OIE) recomme...