Triclosan is a widely used antimicrobial compound commonly incorporated into personal care products, raising significant environmental concerns because of its persistence and toxicity in greywater systems. This research examined the photocatalytic degradation of triclosan in artificial bathroom greywater using zinc oxide nanoparticles that were synthesized using a green method with Pistia stratiotes extract. The nanoparticles...

Purpose Adverse childhood experiences (ACEs) are hypothesized to increase breast cancer risk via social and physiological pathways, yet associations between ACEs and young-onset breast cancer (BC) subtypes–and potential mediators (e.g., adiposity) of these associations–are largely unstudied. We sought to evaluate associations between ACEs and young-onset BC molecular subtypes, and the potential mediating effects of adiposity,...

Purpose Niemann-Pick type C (NPC) disease caused by mutations in cholesterol transporters NPC1 or NPC2 is characterized by cholesterol accumulation in late endosomes/lysosomes (LE/Lys). The activation of alternative cholesterol export routes that can bypass NPC1/2 deficiency could provide therapeutic opportunities. We previously demonstrated that gene depletion of the Rab7-GTPase activating protein (GAP) TBC1D15, which hydroly...

Urban environmental monitoring networks frequently encounter significant data gaps due to sensor malfunctions, environmental disturbances, and communication failures. Reliable approaches to address these gaps are essential for ensuring the continuity and quality of environmental data streams. In this study, we developed a gated attention bidirectional long short-term memory (GA-BiLSTM) model to impute missing data in a dense u...

There is growing evidence that morphological change is a widespread response to the warming climate. The empirical basis for understanding this process has, to date, largely been correlative analyses of morphological time series. However, it is not clear what constitutes sufficient temporal sampling for assessing long-term morphological change. We analyzed two long-term high-quality morphological datasets, one including 33 spe...

Necrotizing enterocolitis (NEC) is the most common surgical emergency in preterm infants; nonetheless, besides supportive measures, no treatment is available. NEC significantly increases length of hospitalization of preterm infants, causes severe morbidity and up to 70% mortality. Despite limited understanding of the underlying mechanisms, prematurity, dysbiosis and an underdeveloped immune system are known to increase the ris...