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Procedural Variation May Contribute to 6-Minute Walk Distance Variability in Real-World Pediatric Pulmonary Arterial Hypertension StudyNARA Subscribed
The six-minute walk test (6MWT) is a common method to assess submaximal exercise capacity in children and adults with pulmonary arterial hypertension (PAH) and other chronic diseases. There is no guideline specifically for 6MWT in children. In this observational pilot study, we evaluated the impact of procedural variations on the outcome of the 6MWT in the real-world clinical setting at pediatric PAH programs. We collected 6MW...
Prolonging survival in good health is a fundamental societal goal. However, the leading determinants of disability-free survival in healthy older people have not been well established. Data from ASPREE, a bi-national placebo-controlled trial of aspirin with 4.7 years median follow-up, was analysed. At enrolment, participants were healthy and without prior cardiovascular events, dementia or persistent physical disability. Disab...
Anthropogenic disturbances affect the health of coral reefs worldwide and may also impact hawksbill ( Eretmochelys imbricata ) foraging areas, potentially decreasing sponge numbers, while increasing macroalgae. Few studies have been conducted to understand energy content of hawksbill prey. We investigated observed ( Geodia neptuni and Kallymenia limminghii ) and potential ( Xestospongia muta and Halimeda opuntia ) hawksbill pr...
Aim The aim of this study was to resolve the phylogenetic placement of island taxa, reconstruct ancestral origins and resolve competing hypotheses of dispersal patterns and biogeographical histories for oceanic island endemic taxa within subgenus Plantago (Plantaginaceae). Location Juan Fernández Islands, the Auckland Islands, Lord Howe Island, New Amsterdam Island, New Zealand, Tasmania, Falkland Islands, Rapa Iti and the Haw...
Antiviral activities of Clinacanthus nutans (Burm.f.) Lindau extract against Cyprinid herpesvirus 3 in koi ( Cyprinus carpio koi)NARA Subscribed
Cyprinid herpesvirus 3 (Cy HV ‐3) or koi herpesvirus ( KHV ) is a virulent viral infection in common carp and koi. The disease has caused global epizootic and economic loss in fish aquaculture and in the wild. Clinacanthus nutans (Burm. f.) Lindau is a well‐known medicinal plant used in Thai traditional medicine. Virucidal effects of the plant extract against human herpes simplex virus have been reported. In this study, C. nut...
Follicle cell processes: a shark thing?NARA Subscribed
Follicle cell processes ( FCP ) are identified in two species of carcharhinid shark (Selachii) but are absent in the little skate Leucoraja erinacea (Batoidea). This suggests that FCPs are either a unique structure that evolved in selachians or were lost by the batoids after their divergence, some 280 mya . The presence of FCPs in the selachians would be consistent with the evolution of large oocytes in this group of animals.
Species that are strong interactors play disproportionately important roles in the dynamics of natural ecosystems. It has been proposed that their presence is necessary for positively shaping the structure and functioning of ecosystems. We evaluated this hypothesis using the case of the world's largest parrotfish ( Bolbometopon muricatum ), a globally imperiled species. We used direct observation, animal tracking, and computer...