Aim Stream captures are implicated as drivers of speciation in many groups of lotic fishes. In the southeastern United States, numerous stream‐dwelling animals possess restricted trans‐divide populations at localities where quiescent geologic features intersect drainage divides, suggesting potential evidence for inter‐basin vicariance via stream capture. However, there has not yet been a comprehensive quantitative biogeographi...

We combine published and new mineralogical data on most major taxa of brachiopods from all over the world, to investigate patterns and controls on brachiopod carbonate mineralogy. Measurements of 1726 specimens in 162 species (including 56 fossil species) ranged from 79°N to 74°S and from intertidal to almost 4000 m deep. Calcareous brachiopods mostly create strong resilient valves of very low‐Mg calcite ( = 1.3 wt% MgCO 3 )....

To study the impact of necroptosis-induced chronic inflammation on age-related diseases and aging, two knockin mouse models ( Ripk3 -KI and Mlkl -KI) were generated that overexpress two genes involved in necroptosis ( Ripk3 or Mlkl ) when crossed to Cre transgenic mice. Crossing Ripk3 -KI or Mlkl -KI mice to albumin-Cre transgenic mice produced hepatocyte specific hRipk3 -KI or hMlkl -KI mice, which express the two transgenes...

To understand the potential of forests to adapt to wildfire, we studied the genetic architecture of fire-related structural, damage and recovery traits in a globally important Australian forest tree species, Eucalyptus globulus . Fourteen traits were evaluated in an outcrossed F 2 population in a field trial in Tasmania, Australia, which was burnt by a wildfire 14 years after planting. The trial also included open-pollinated f...

Multiple system atrophy (MSA) is a fatal neurodegenerative disease of unknown etiology characterized by widespread aggregation of the protein alpha-synuclein in neurons and glia. Its orphan status, biological relationship to Parkinson’s disease (PD), and rapid progression have sparked interest in drug development. One significant obstacle to therapeutics is disease heterogeneity. Here, we share our process of developing a clin...