S. Jayasinghe results 36
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Leveraging polygenic risk scores to infer causal directions in genotype-by-environment interactions between complex traitsNARA Subscribed
Most existing genotype-by-environment interaction (G×E) methods assume a known causal direction as an assumption that often does not hold and can lead to biased estimates and spurious findings. To address this, we introduce the Genetic Causality Inference Model (GCIM), a novel approach designed to infer causal directions in G×E studies. GCIM integrates polygenic risk scores (PRS) for both the exposure and the outcome to streng...
Coastal fisheries, mainly characterized by small pelagic species, are significant on the west coast of Sri Lanka in terms of livelihood and food security. However, currently, the fishery has faced numerous challenges, particularly with the stock depletion allied with poor management practices. The present study was carried out using the time series data of 2001–2020 on the west coast of Sri Lanka representing four fisheries di...
Pole and line fishery is one of the oldest traditional techniques employed in tuna fishing in the Indian Ocean including Sri Lanka, which is mainly targeted to exploit skipjack tuna. This fishery has fallen to a relatively low level of significance during the past three decades. The potentialities for the expansion of pole and line fishery in Sri Lanka are regained with the possible negative consequences allied with the drift...
Blue whales Balaenoptera musculus are the most abundant and widely distributed cetacean species in Sri Lankan waters. A vessel-based opportunistic line transect survey focusing on marine mammals was conducted in Sri Lankan waters between 24 June to 12 July 2018, while an ecosystem survey was performed by the R/V Dr. Fridtjof Nansen. The entire transect length was 2090 km within an area of 3895 km2. Overall, 72% (n = 57) of blu...
Prolonging survival in good health is a fundamental societal goal. However, the leading determinants of disability-free survival in healthy older people have not been well established. Data from ASPREE, a bi-national placebo-controlled trial of aspirin with 4.7 years median follow-up, was analysed. At enrolment, participants were healthy and without prior cardiovascular events, dementia or persistent physical disability. Disab...
This study investigated whether allochthonous inputs generated by cattle and water buffaloes grazing in the catchment or wading in the water in small village reservoirs of Sri Lanka can make a significant effect on yields from culture-based fisheries of those reservoirs. The analysis is based on limnological data of 37 randomly selected reservoirs. As culture-based fish yield data were available over the 2002 - 2003 period onl...
As in many tropical reservoir fisheries, the major fishing gear in the reservoirs of Sri Lanka is gillnet. Gillnets of a wide range of stretched mesh sizes (6.9 - 11.4 cm) are used in individual boats in Sri Lankan reservoirs targeting mainly two exotic cichlid species, Oreochromis mossambicus and O. niloticus, which dominate the fisheries accounting for over 80% of the landings. Although the filament characteristics and dimen...
Stilt fishing is a unique fish catching method confined only to southern coast of Sri Lanka from Galle to Matara. Stilt fishermen sitting on a cross bar called “Petta” tied to vertical pole planted in the reef and carrying out rod and line fishing are a Sri Lankan icon that attracts local and foreign tourists’ attention. This small-scale, seasonal fishing method has a long history and fishers use traditional ecological knowled...