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Low circulating adropin concentrations predict increased risk of cognitive decline in community-dwelling older adultsNARA Subscribed
The secreted peptide adropin is highly expressed in human brain tissues and correlates with RNA and proteomic risk indicators for dementia. Here we report that plasma adropin concentrations predict risk for cognitive decline in the Multidomain Alzheimer Preventive Trial (ClinicalTrials.gov Identifier, NCT00672685; mean age 75.8y, SD = 4.5 years, 60.2% female, n = 452). Cognitive ability was evaluated using a composite cognitiv...
Enriched atmospheric CO 2 and defoliation: effects on tree chemistry and insect performanceNARA Subscribed
We examined the effects of CO 2 and defoliation on tree chemistry and performance of the forest tent caterpillar , Malacosoma disstria . Quaking aspen ( Populus tremuloides ) and sugar maple ( Acer saccharum ) trees were grown in open‐top chambers under ambient or elevated concentrations of CO 2 . During the second year of growth, half of the trees were exposed to free‐feeding forest tent caterpillars, while the remaining tree...
CO 2 ‐mediated changes in aspen chemistry: effects on gypsy moth performance and susceptibility to virusNARA Subscribed
We investigated the effects of long‐term CO 2 enrichment on foliar chemistry of quaking aspen ( Populus tremuloides ) and the consequences of chemical changes for performance of the gypsy moth ( Lymantria dispar ) and susceptibility of the gypsy moth to a nucleopolyhedrosis virus (NPV). Foliage was collected from outdoor open‐top chambers and fed to insects in a quarantine rearing facility. Under enriched CO 2 , levels of leaf...
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