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Infectious haematopoietic necrosis virus (IHNV) causes devastating economic losses in salmonid aquaculture and effective control measures are urgently needed. This study investigates the anti‐IHNV potential of postbiotics derived from Lactiplantibacillus plantarum . The crude postbiotic extract (PBP20o) and a neutralized version (PBP20a) were evaluated for cytotoxicity and antiviral activity in epithelioma papulosum cyprini (E...
Osmorespiration of marble goby (Oxyeleotris marmorata) juveniles under different background coloursNARA Subscribed
This study examined the oxygen consumption and ammonia excretion rates of fed marble goby ( Oxyeleotris marmorata ) juveniles (mean [± standard deviation] body weight 25.5 ± 0.5 g) acclimatised for 2 h or 24 h under different background colours (dark grey, light grey, black, red, white, deep green, blue and transparent). Two-way permutational multivariate analysis of variance (PERMANOVA) analysis revealed that oxygen consumpti...
Interpretable deep learning reveals spatiotemporal MRI features of brain aging that align with neurodegenerationNARA Subscribed
Cortical thinning and atrophy are hallmarks of brain aging that have been characterized using magnetic resonance imaging (MRI). Brain aging involves many neuroanatomic features whose effects on brain structure remain unexplored. To address this challenge, we trained interpretable deep neural networks (DNNs) to estimate brain age (BA) from T 1 -weighted ( T 1 w) MRI. By identifying MRI features unapparent to humans, DNNs can fi...
Alzheimer’s disease (AD) disproportionately affects women and carriers of the apolipoprotein E ε4 allele (APOE4), yet little is known about how sex and APOE interact to influence white matter (WM) integrity during disease progression. We integrated diffusion MRI and matched blood transcriptomic data to investigate these interactions and their underlying biological mechanisms. WM microstructure was quantified using diffusion te...
Soyasaponin intolerance is common in ancient fish species, making them susceptible to enteritis caused by dietary soybean meal. β,β-Dimethylacrylshikonin is the key active monomer found in Lithospermum erythrorhizon and is known for its multiple pharmacological activities. However, its effect on soybean meal-induced enteritis remains unknown. The administration of 2 g/kg of β,β-Dimethylacrylshikonin (LE) effectively alleviated...
Appetitive responses of purple mud crab (Scylla tranquebarica) towards formulated diet leachates made of various marine protein sourcesNARA Subscribed
The present study evaluated the attractability of diets formulated with various marine protein sources to the Scylla tranquebarica by examining their appetitive responses towards the diets’ leachates. Six experimental diets were formulated using fish meal (FM), sergestid shrimp meal (SSM), and squid meal (SQM), which were FM100 (100% FM protein), SSM100, SQM100, FM50SSM50 (50% FM and 50% SSM proteins), FM50SQM50, and SSM50SQM5...