Biocontrol is a key strategy for disease control, as it is environmentally friendly and widely applicable. This review elaborates on biocontrol in aquaculture, particularly in shrimp culture. Biocontrol in shrimp culture mainly relies on four strategies: (i) direct kill pathogen by Bdellovibrio or bacteriophages; (ii) suppression of intestinal pathogens with probiotics; (iii) reduction of environmental pathogens via probiotics...