White spot syndrome virus (WSSV) remains a persistent and significant threat to the global shrimp aquaculture industry. However, its pathogenic mechanisms remain incompletely understood, and no effective intervention strategies are currently available. In this study, we investigated the functional role of VP53B, an envelope structural protein of WSSV, using a combination of infection bioassays, protein structure prediction, pr...

During the past decade, metagenomics became a method of choice for the discovery of novel viruses. However, host assignment for uncultured viruses remains challenging, especially for archaeal viruses, which are grossly undersampled compared to viruses of bacteria and eukaryotes. Here, we assessed the utility of CRISPR spacer targeting, tRNA gene matching and homology searches for viral signature proteins, such as major capsid...

Bow shape has been recognized as an important factor influencing the seakeeping performance and added resistance of ships. This paper presents a numerical comparative study on added resistance and seakeeping of model ships with ‘X-bow’ and a wave-piercing monohull in regular head waves using a computational fluid dynamics (CFD) software. Different wave heights, wavelengths and forward speeds are considered in the systematic in...