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Transformation of Ritonavir Nanocrystal Suspensions into a Redispersible Drug Product via Vacuum Drum DryingNARA Subscribed
The present study explored vacuum drum drying (VDD) as potential drying technique for the solidification of crystalline ritonavir nanosuspensions prepared by wet-ball milling. In detail, the impact of drying protectants (mannitol, lactose, trehalose) added to the ritonavir nanosuspension was assessed in dependence of the drum temperature with respect to processibility via VDD, resulting intermediate powder properties, remainin...
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