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The influence of station-to-station line orientation on sea current speed observations using Coastal Acoustic Tomography (CAT) was quantitatively investigated. For this purpose, we conducted CAT experiments at five stations in Yeosu Bay, South Korea. Through these experiments, the sea current speeds were estimated along a total of six tomographic observation lines with different orientations, and the results were compared with...
Observation of current speeds in coastal seas is crucial because it can provide useful information for ship operations, fishing activities, and rapid responses to marine disasters. Coastal acoustic tomography (CAT) is a technology that can continuously monitor environmental changes such as current velocity and water temperature using reciprocal acoustic signals between CAT stations in coastal seas. This technology is different...
Purpose Three-dimensional (3D) ultrasound localization microscopy (ULM) using a 2-D matrix probe and microbubbles (MBs) has recently been proposed to visualize microvasculature in three spatial dimensions beyond the ultrasound diffraction limit. However, 3D ULM has several limitations, including: (1) high system complexity, (2) complex MB flow dynamics in 3D, and (3) extremely long acquisition time that had to be addressed. Me...
Insignificant effects of loss of heterozygosity in HLA in the efficacy of immune checkpoint blockade treatmentNARA Subscribed
Background It is assumed that loss of heterozygosity and allelic copy loss in HLA gene is associated with poor response rates in immune checkpoint inhibitor treatment. H-owever, the accurate extents or consistency in cancer types have not been explored. Objective The goal of this study is to investigate quantitative relationship between HLA allelic copy loss and response rates to immune checkpoint inhibitors. Also, tumor micro...