The Kulanaokuaiki Tephra Unit 3 (900 C.E.) was a subplinian basaltic scoria eruption, the largest known to have occurred at Kīlauea’s summit. The initiation mechanism and cause(s) of this highly hazardous eruption remain poorly understood, particularly as this style of activity has not been observed in the modern period. We use olivine diffusion timescales from Fe-Mg and lithium zoning to assess magma storage timescales and ev...

Albumin, a highly biocompatible protein, has been utilized in the construction of anti-cancer drugs for the treatment of various cancers. However, albumin-based nanomedicines still face several clinical challenges, including low stability in the bloodstream, non-specific targeting ability, and lack of controlled release capability. To address these limitations, we developed a multiprotein-based nanomedicine for targeted chemot...

Purpose Osteonecrosis of the femoral head (ONFH) requires effective removal of necrotic tissue to improve surgical outcomes. Conventional curettes often fail to address clinical needs due to limitations in cutting capability, strength, and adaptability. This study introduces a disposable multi-angle eccentric curette designed to enhance necrotic bone removal during core decompression surgery. Methods The curette was designed w...