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Molecular characterization of extended-spectrum β-lactamases-producing Escherichia coli isolated from patients with bacteremiaNARA Subscribed
Bacteremia is a major health problem that affects millions of people worldwide. E. coli is one of the main pathogens associated with bacteremia and its resistance to the antimicrobial drugs, including β-lactams, has significantly increased in recent years. In view of the above, our objective was to determine the antimicrobial resistance profile of 60 E. coli isolates obtained from patients with bacteremia, as well as to charac...
Total plasma N-glycomic patterns of COVID-19 diseaseNARA Subscribed
Total plasma N -glycans alter in disease states, with few studies focused on COVID-19. A discovery cohort of 310 COVID-19 patients, replicated with 97 COVID-19 patients and tested with 100 COVID-19 patients, was used to unearth the N -glycans capable of distinguishing infection, as well as prognosis of intensive care unit (ICU) admission and mortality. All significant bisected glycans were decreased in patients compared to con...
Cannabigerol and standardized full-spectrum cannabis extract effects in acute and chronic inflammatory pain modelsNARA Subscribed
Background Chronic inflammatory pain is associated with persistent sensory and immune dysregulation. We evaluated the therapeutic efficacy of two cannabinoids formulations—Cannabigerol (CBG) and Standardized Full-Spectrum Cannabis Extract (FULL) in a preclinical model of acute and Chronic inflammatory pain and examined their effects on peripheral and central inflammatory mediators. Methods Cannabinoid analgesic effects were as...
Climatic and Hydrological Changes Drive Contemporary Fire Regime Transitions in the World's Largest WetlandNARA Subscribed
Tropical wetlands have historically been resilient to fire, but ongoing climate and hydrological changes are undermining this stability. Here, we provide robust multi‐decadal evidence (1985–2024) of structural changes in the contemporary fire regime of the Pantanal, the world's largest wetland, associated with hydroclimatic disruption. We investigated changes in burned area, mean fire size, and fire seasonality using hydrologi...
Submaximal walking increases MicroRNA-126 and angiogenic markers in men and women with peripheral arterial diseaseNARA Subscribed
Purpose Vascular dysfunction is a pathophysiological mechanism in peripheral artery disease (PAD). PAD patients exhibit reduced circulating expression of microRNA-126 (c-miRNA-126) and VEGF. Submaximal walking (SW) is recommended in PAD because it increases walking capacity, partially by improving vascular regulation, which can be observed after a walking session. Nevertheless, previous studies were conducted with maximal walk...
This research outlines the integration of machine learning, citizen science, environmental DNA (eDNA), and other emerging technologies to enhance marine biodiversity and invasive alien species monitoring, discussed during a summer school organized by several European projects in June 2025. Furthermore, monitoring approaches are increasingly complemented by remote sensing, drones, and machine learning to expand spatial coverage...
Aim We investigate the distribution of dispersal modes — endozoochory (via animal ingestion), synzoochory (via animal seed accumulation) and anemochory (via wind)—and seed mass of woody plants across Brazilian ecosystems, testing whether their relative abundance in local plant communities could be predicted by climate, edaphic factors and dispersal agents (e.g., the main vectors moving seeds). We expected climate to be the mai...