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Development of molecular diagnostic test to quantify Rhizobium leguminosarum bv. viciae (rhizobia group E/F) in soilNARA Subscribed
Aims Rhizobia are essential for nitrogen fixation in legumes. The current method for enumerating rhizobia in soil by the Most Probable Number (MPN) method is costly and time consuming. This paper describes the development of a qPCR test to quantify Rhizobium leguminosarum bv. viciae (Rlv) in soil. Methods TaqMan probe and primers were developed . Specificity of qPCR was confirmed against Rlv and non-target rhizobia and compare...
Purpose Hydrogen cation (H + ) accumulation is exacerbated in hypoxia. Sodium bicarbonate (NaHCO 3 ) ingestion can reduce fatigue associated with high-intensity exercise performance by counteracting H + ion accumulation. The present study aimed to determine the effect of 0.3 g·kg − 1 NaHCO 3 mini-tablets in a carbohydrate hydrogel on 40 km cycling time trial (TT) performance in trained male cyclists in acute hypoxia. Methods F...
Marine megafauna species are affected by a wide range of anthropogenic threats. To evaluate the risk of such threats, species’ vulnerability to each threat must first be determined. We build on the existing threats classification scheme and ranking system of the International Union for Conservation of Nature (IUCN) Red List of Threatened Species by assessing the vulnerability of 256 marine megafauna species to 23 at‐sea threat...
Protein kinase C iota (PKCι) and pVHL are both needed for lysosomal degradation of α5 integrin in renal carcinoma cellsNARA Subscribed
Background von Hippel-Lindau (VHL) hereditary cancer syndrome is caused by mutations in the VHL tumor suppressor gene and is characterized by a predisposition to form various types of tumors, including renal cell carcinomas, hemangioblastomas, and pheochromocytomas. The protein products of the VHL gene, pVHL, are part of an ubiquitin ligase complex that tags hypoxia inducible factor alpha (HIF-α) for proteosomal degradation. p...
Proteolytic pathways in bovine milk containing β-CN A1 or A2NARA Subscribed
Voxel-wise insights into early Alzheimer’s disease pathology progression: the association with APOE and memory declineNARA Subscribed
Longitudinal investigation of the Apolipoprotein E (APOE) genotype’s impact on Alzheimer’s disease (AD) biomarker progression, focusing on amyloid beta (Aβ) accumulation and gray matter (GM) atrophy, integrating cognitive decline and baseline levels. Longitudinal florbetapir-PET and T1-weighted MRI data from 100 cognitively normal (CN) and mild cognitive impaired (MCI) participants both with considerable global Aβ accumulation...