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Fire–Moisture Interactions Shape Recovery Trajectories Across Temperate Vegetation CommunitiesNARA Subscribed
The recovery of vegetation following fire is increasingly shaped by concurrent climate‐driven hydrological extremes, such as drought and extreme precipitation. Under these multi‐disturbance scenarios vegetation communities are likely to show different recovery thresholds and trajectories of change, but this is yet to be fully understood or quantified. We used the Greater Blue Mountains World Heritage Area in south‐eastern Aust...
Introduction Toxicologists may use high dose n-acetylcysteine (HD-NAC) for early-treated high-risk acetaminophen ingestions (EHRAI) given concerns over standard NAC (S-NAC) dosing’s efficacy. We utilize the novel, clinically relevant outcome of mean additional 16-hour NAC maintenance infusions (NMI) to evaluate differences in treatment duration for EHRAI patients treated with S-NAC versus HD-NAC. Methods Retrospective multista...
High incidence of estrous cycle irregularities in heterogeneous stock (HS) rats is associated with footshock-resistant cocaine intakeNARA Subscribed
Rationale Hormonal fluctuations throughout the estrous cycle are hypothesized to influence drug-related behaviors. Preclinical models show that some cocaine-related behaviors are influenced by the estrous cycle. However, the extent to which the estrous cycle modulates cocaine self-administration in outbred heterogeneous stock (HS) rats is unknown. Objectives We aimed to examine the relationship between estrous phases and cocai...
Preventing the spread of small, cryptic invasive reptiles poses an ongoing challenge for conservation and biosecurity worldwide. Physical exclusion barriers offer a potentially low-cost, non-toxic tool for limiting dispersal, but their effectiveness depends on, among other factors, a detailed understanding of how surface properties influence animal movement. We tested four commonly available fencing materials—polypropylene fab...
Voxel-wise insights into early Alzheimer’s disease pathology progression: the association with APOE and memory declineNARA Subscribed
Longitudinal investigation of the Apolipoprotein E (APOE) genotype’s impact on Alzheimer’s disease (AD) biomarker progression, focusing on amyloid beta (Aβ) accumulation and gray matter (GM) atrophy, integrating cognitive decline and baseline levels. Longitudinal florbetapir-PET and T1-weighted MRI data from 100 cognitively normal (CN) and mild cognitive impaired (MCI) participants both with considerable global Aβ accumulation...
“Single Model initial-condition Large Ensembles” (SMILEs) conducted with Earth system models have transformed our ability to quantify internal climate variability and forced climate change at local and regional scales. An important consideration in their experimental design is the choice of initialization procedure as this influences the duration of initial-condition memory, with implications for interpreting the temporal evol...
Germline copy number variants and endometrial cancer riskNARA Subscribed
Known risk loci for endometrial cancer explain approximately one third of familial endometrial cancer. However, the association of germline copy number variants (CNVs) with endometrial cancer risk remains relatively unknown. We conducted a genome-wide analysis of rare CNVs overlapping gene regions in 4115 endometrial cancer cases and 17,818 controls to identify functionally relevant variants associated with disease. We identif...
Artificial Light Increases Nighttime Prevalence of Predatory Fishes, Altering Community Composition on Coral ReefsNARA Subscribed
Artificial light at night (ALAN) is an anthropogenic pollutant that is intensifying and expanding in marine environments, but experimental studies of community‐level effects are generally lacking. The inshore, shallow, and clear‐water locations of coral reefs and their diverse photosensitive inhabitants make these ecosystems highly susceptible to biological disturbances; at the same time, their biodiversity and accessibility m...