E. Mueller results 140
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Effects of repeated low-dose LSD on neuropsychological functioning in adults with ADHD: a randomized placebo-controlled studyNARA Subscribed
Rationale Attention-deficit hyperactivity disorder (ADHD) shows substantial heterogeneity in symptoms and cognitive deficits. According to the Triple Pathway Model, this variability may stem from impairments in three neuropsychological domains: inhibition, motivation, and temporal processing. Repeated low-dose administration of psychedelics is being explored as a treatment for ADHD, but evidence from controlled studies in this...
16p11.2 duplication and NMDA receptor antagonism have distinct impacts on reward learning and decision makingNARA Subscribed
Rationale 16p11.2 duplication is associated with numerous neuropsychiatric conditions at a genome-wide level, including psychosis. Mice modeling 16p11.2 duplication may provide important insights into cognitive risk factors, in particular in reward-guided decision making. NMDAR function has also been implicated in psychosis phenotypes, but whether these phenotypes differ by genetic risk factor is unknown. Objectives We aimed t...
Soil Organic Carbon Improves Crop Yield and Yield ResilienceNARA Subscribed
Increasing soil organic carbon (SOC) has been proposed as a strategy to promote crop yield resilience under extreme hydroclimatic stress, particularly drought, due to its positive effect on soil available water‐holding capacity. We analyze how SOC mediates the relationship between US rainfed crop yields (1981–2020) and growing season hydroclimatic conditions—defined by soil water supply and atmospheric water demand—over 67,000...
Beyond strength: dietary nitrate augments self-selected functional mobility after resistance training in middle-aged adultsNARA Subscribed
This study aimed to assess whether dietary nitrate supplementation with resistance training (RT) augments gait performance and functional mobility in inactive middle-aged and older adults. We hypothesized that combining nitrate-rich beetroot juice (BRJ) with RT would yield improvements in gait and functional mobility compared to RT with nitrate-depleted beetroot juice placebo (PLA) supplementation. In this 12-week, randomized,...
Robust Trend Estimation From Temporally Irregular Recreational Fisheries Surveys: A Panel Modeling Framework for Sparse Time SeriesNARA Subscribed
Monitoring of recreational fisheries faces ongoing challenges due to irregular data collection and sampling gaps. We used a robust statistical approach combining cross‐sectional panel modeling with generalized linear models to analyze discontinuous time series data. We modeled recreational boating patterns across four distinct Western Australian locations using camera monitoring data (2011–2014), and integrated weather conditi...
Combined resistance mechanisms leading to high-level of cefiderocol resistance among NDM-like producing E. coli ST167 clinical isolatesNARA Subscribed
Summary Purpose A series of NDM-producing Escherichia coli ST167 clinical isolates exhibiting resistance to cefiderocol (FDC), with no previous exposure to this antibiotic, were analyzed in this study. Methods The antimicrobial susceptibility testing and phenotypic detection of resistance patterns (Rapid Cefiderocol NP test and MIC determination) were performed for all tested isolates. Their entire genomes were sequenced by us...
In drylands, where water scarcity limits vascular plant growth, much of the primary production occurs at the soil surface. This is where complex macro‐ and microbial communities, in an intricate bond with soil particles, form biological soil crusts (biocrusts). Despite their critical role in regulating C and N cycling in dryland ecosystems, there is limited understanding of the fate of biologically fixed C and N from biocrusts...
Methane (CH 4 ) is a potent greenhouse gas (GHG) with atmospheric concentrations that have nearly tripled since pre‐industrial times. Wetlands account for a large share of global CH 4 emissions, yet the magnitude and factors controlling CH 4 fluxes in tidal wetlands remain uncertain. We synthesized CH 4 flux data from 100 chamber and 9 eddy covariance (EC) sites across tidal marshes in the conterminous United States to assess...
Rationale Corticotropin-releasing factor (CRF), the apical stress-inducing hormone, exacerbates stress and addictive behaviors. TCAP-1 is a peptide that directly inhibits both CRF-mediated stress and addiction-related behaviors; however, the direct action of TCAP-1 on morphine withdrawal-associated behaviors has not previously been examined. Objective To determine whether TCAP-1 administration attenuates behavioral and physiol...
Reading tea leaves worldwide: Decoupled drivers of initial litter decomposition mass‐loss rate and stabilizationNARA Subscribed
The breakdown of plant material fuels soil functioning and biodiversity. Currently, process understanding of global decomposition patterns and the drivers of such patterns are hampered by the lack of coherent large‐scale datasets. We buried 36,000 individual litterbags (tea bags) worldwide and found an overall negative correlation between initial mass‐loss rates and stabilization factors of plant‐derived carbon, using the Tea...