Background The Passiflora genus presents a representative variability of passion fruit species with food, pharmacological and ornamental potential. To understand this genetic variability, it is essential that genetic resources are well characterized for future use in breeding and conservation programs. The aim of this study was to investigate for the first time the diversity genetic and structure population of 88 Passiflora ge...

The anesthetic management of female dogs with mammary neoplasia, usually classified as ASA II and undergoing invasive procedures such as mastectomy and ovariohysterectomy, requires effective sedation and anesthetic stability due to the increased anesthetic risk associated with advanced age and underlying disease. In this context, this study aimed to evaluate the sedative effects and reduction in anesthetic requirements of a fu...

Leptospirosis is a neglected zoonosis with significant impact on public and veterinary health, with equines acting as potential maintenance hosts of infection. This study aimed to investigate the seroprevalence of Leptospira in Lavradeiro horses under semi-feral conditions in Indigenous communities in the state of Roraima, Brazil. A total of 387 serum samples were subjected to the microscopic agglutination test (MAT), using an...

Nannotrigona testaceicornis are essential pollinators for biodiversity maintenance and agricultural production. However, during foraging in agroecosystems, they may be exposed to residues of bioinsecticides used for pest management. Thus, this study evaluated the toxicity of the commercial product AzaMax® (azadirachtin) to the stingless bee N. testaceicornis . Adult worker bees were exposed to this bioinsecticide by contact an...

Mimosa L. comprises approximately 620 species of socioeconomic and environmental importance, with about half occurring in the Brazilian Cerrado. Despite this diversity, cytogenetic studies in the genus remain limited, with most restricted to chromosome counts. We investigated 11 populations of seven Mimosa species, focusing on the heterochromatin distribution (CMA + bands), and nuclear DNA content. Polysomaty was observed in r...

Multiform glioblastoma (GBM) is the most aggressive primary brain tumor, associated with high heterogeneity, treatment resistance, and poor survival. Temozolomide (TMZ), although the main chemotherapeutic agent used, shows limited efficacy due to low solubility, chemical instability, and acquired resistance. In this context, nanostructured systems can enhance their antitumor efficacy. This study aimed to develop and characteri...

Aim We investigate the distribution of dispersal modes — endozoochory (via animal ingestion), synzoochory (via animal seed accumulation) and anemochory (via wind)—and seed mass of woody plants across Brazilian ecosystems, testing whether their relative abundance in local plant communities could be predicted by climate, edaphic factors and dispersal agents (e.g., the main vectors moving seeds). We expected climate to be the mai...

Diabetes mellitus (DM) is a chronic metabolic disorder characterized by persistent hyperglycemia that may impair testicular function, including spermatogenesis and steroidogenesis. Creatine, an endogenously synthesized nitrogenous compound and one of the main reservoirs in the testes, is widely used, particularly among men. However, evidence regarding its effects on male reproductive health, especially under DM, remains limite...

Purpose Quantifying collagen in histological slides is essential for diagnosing and monitoring fibrosis. However, the combination of PicroSirius Red staining with polarized light microscopy, one of the standard techniques, requires expensive equipment and time-consuming procedures. This study investigated whether supervised machine learning algorithms applied to bright-field images could provide an automated and accurate metho...