Acupuncture is used worldwide to treat migraine, but its scientific mechanism remains unclear. Here, we report a 1 H NMR metabolomics study involving 40 migraine patients and 10 healthy individuals randomly receiving acupuncture or sham acupuncture, followed by machine learning techniques and functional analysis. We found that acupuncture at acupoints particularly enhanced anaerobic glycolysis and modified mitochondrial functi...

Epigenetic mechanisms are integral to plant growth, development, and adaptation to environmental stimuli. Over the past two decades, our comprehension of these complex regulatory processes has expanded remarkably, producing a substantial body of knowledge on both locus-specific mechanisms and genome-wide regulatory patterns. Studies initially grounded in the model plant Arabidopsis have been broadened to encompass a diverse ar...

This study investigated the effects of replacing dietary fish meal (FM) with golden apple snail ( Pomacea canaliculata ) meat meal (PCM) on growth performance, non-specific immunity and intestinal health of juvenile Chinese mitten crab ( Eriocheir sinensis ). Four hundred juvenile Chinese mitten crabs (2.39 ± 0.03) g were randomly distributed into five groups in quadruplicate (20 crabs per tank), and each group was fed with di...