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Targeting Mitochondrial Dysfunction in Acute Organophosphate Toxicity: A Preliminary Evaluation of Cyclosporine ANARA Subscribed
Background Organophosphate (OP) compounds are widely used agricultural chemicals that pose significant public health and chemical threat concerns due to their neurotoxic effects. Although OP toxicity has classically been attributed to acetylcholinesterase inhibition and cholinergic crisis, emerging evidence suggests mitochondrial dysfunction may represent an additional and clinically relevant mechanism of injury. Experimental...
N -(1,3-Dimethylbutyl)- N '-phenyl- p -phenylenediamine (6PPD) and its ozonation product, 6PPD-quinone (6PPD-Q), are contaminants of global concern due to their widespread occurrence and acute toxicity to aquatic organisms. Conventional treatment methods often fail to its complete removal in water. Peroxyacetic acid is extensively employed in advanced oxidation processes; however, it relies generally on ultraviolet light irrad...
Precision measurement of the Ds*+-Ds+ meson mass differenceNARA Subscribed
Sepsis survivors frequently experience post-discharge physical function decline and encounter logistical barriers to participation in traditional outpatient rehabilitation. This pilot study examined the feasibility, safety, and preliminary efficacy of a remotely delivered, home-based exercise program on physical function in older sepsis survivors. In this single-blinded, randomized controlled trial (RCT), sepsis survivors aged...