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Deviations from additivity in APOE4-mediated late-onset Alzheimer’s disease risk across races and ethnicitiesNARA Subscribed
APOE ’s ε4 haplotype ( APOE4 ) is late onset Alzheimer’s disease’s (LOAD) strongest genetic risk factor. Therefore, accurately modeling APOE4 ’s effect is critical to understanding LOAD. This is especially important as APOE4 odds ratios (OR) vary across racial and ethnic (R/E) groups. We analyzed the APOE4 -LOAD association in 3,196 East Asian, 31,105 non-Hispanic White (White), 1,646 Hispanic and Latino (Hispanic), and 6,068...
Spatio-temporal dynamics of Lagos flooding: comparative multi-parameter analysis of 2011 and 2021 eventsNARA Subscribed
This study examines changes in flooding characteristics in Lagos, Nigeria, through comparative analysis of major flooding events in July 2011 and July 2021. Satellite data from NASA’s IMERG and MODIS platforms were used to analyse precipitation patterns, aerosol concentrations, and land surface temperatures through spatial autocorrelation and regression analysis. The comparison reveals substantial changes in flood characterist...
Underground hydrogen storage (UHS) in depleted gas reservoirs is an effective strategy for balancing renewable energy supply and demand, with cushion gases being used to maintain storage pressure. Here CO 2 is investigated as a cushion gas via measurements of the dispersion between hydrogen and CO 2 in a (Bentheimer sandstone) rock core, performed at reservoir-relevant conditions using a novel core flooding apparatus. Such dat...