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A practical guide to investigating biomolecular condensates: a comment from the plant communityNARA Subscribed
Biomolecular condensates formed through phase separation have emerged as a central principle of cellular organization, enabling the dynamic regulation of gene expression, signaling, metabolism, and stress responses. While early conceptual advances in condensate biology have largely originated from animal and in vitro systems, plant cells present a unique set of biological and technical challenges, including rigid cell walls, t...
Untangling the Overexploitation Trap: Governance, Politics of Concepts, and the Sustainability Claims of Chilean Southern HakeNARA Subscribed
Despite a 2013 legal reform introducing polycentric governance and an active Marine Stewardship Council (MSC) certification, persistent overexploitation of Chilean Southern hake ( Merluccius australis ) raises fundamental questions about how institutional arrangements embedding participatory management and science‐based decision‐making actually shape management outcomes. We systematically analyzed all 54 meeting minutes of Chi...
Seriola dumerili digestive capacityNARA Subscribed
Protamine nanocapsules as gene delivery carriers for the treatment of intraocular tumorsNARA Subscribed
Uveal melanoma is the most common primary intraocular tumor in adults that appears mainly in the choroid, ciliary body, or iris. Standard non-surgical treatment consists of radiotherapy and chemotherapy by intravitreal injection of drugs, which is hampered by unpleasant side effects and high recurrence rate. As an alternative strategy, gene therapy has the capacity of targeting specific pathways in cancer cells by introducing...
Background The oxylipins 10-HpOME and 7,10-DiHoME derive from oleic acid and have been extensively studied for their ability to regulate contractions, microcolony formation and biofilm formation in the model organism Pseudomonas aeruginosa . Methods and results Xylella fastidiosa subsp. pauca strain de Donno has been reported to produce 10-HpOME and 7,10-DiHOME in vivo when inoculated in the model plant Nicotiana tabacum or in...
Epidermolysis bullosa is a rare genetic disorder characterized by extreme mucocutaneous fragility. The healthcare coverage in Argentina is divided into the public sector, social security, and the private sector. This study examines how this segmentation affects the socio-healthcare management of patients with EB, identifying barriers and challenges. A descriptive phenomenological qualitative design was employed. The sample inc...