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Brazil is a country with an approximate 50% prevalence rate of carbapenem-resistant Pseudomonas aeruginosa (CR-PA). Therefore, monitoring the spread of high-risk clones from complex genotypes of CR-PA isolates is crucial for developing effective strategies to control antimicrobial resistance. In the present study, we aimed to evaluate the dissemination of high-risk clones P. aeruginosa carrying bla KPC-2 in Brazil. In this stu...
Air pollution is a major environmental risk to public health, strongly associated with cardiovascular and respiratory diseases. According to the World Health Organization, at least 99% of the global population lives in areas that do not meet its air-quality guidelines. PM $$_{2.5}$$ 2.5 variability reflects the interaction between local emission sources and meteorological processes that regulate near-surface dispersion and acc...
Pollinators are important to humans and nature due to their role in ecosystem functioning and services. Research on the effects of pollinator management in protected areas is insufficient compared with that on farmlands and urban areas, potentially hindering appropriate policy implementation. We addressed this knowledge gap by conducting a data‐based synthesis on measures to promote pollinators (especially bees, butterflies, a...
Septoria tritici blotch (STB), caused by Zymoseptoria tritici , is one of the most damaging foliar diseases of bread wheat ( Triticum aestivum L.), leading to yield losses of up to 50% under favorable conditions and increasing reliance on synthetic fungicides. In this study, the antifungal activity of essential oil (EO) and hydrosol (the aqueous phase obtained as a by-product of hydrodistillation) derived from a local Algerian...
Early-pregnancy exposure to air pollution and stillbirth in São Paulo, Brazil – results from the FetRisks case-control studyNARA Subscribed
Stillbirth remains a major public health concern, particularly in urban settings with persistent air pollution, while evidence remains limited in middle-income countries. This study aims to examine the association between prenatal exposure to fine particulate matter (PM2.5) PM2.5 and stillbirth in São Paulo, Brazil. Case-control study including 348 antepartum stillbirths and 419 live births recruited from 14 public hospitals....
Aim We investigate the distribution of dispersal modes — endozoochory (via animal ingestion), synzoochory (via animal seed accumulation) and anemochory (via wind)—and seed mass of woody plants across Brazilian ecosystems, testing whether their relative abundance in local plant communities could be predicted by climate, edaphic factors and dispersal agents (e.g., the main vectors moving seeds). We expected climate to be the mai...
Aluminum (Al³⁺) accumulates in the brain and has been linked to neurodegeneration. When combined with citrate, its absorption increase, raising the risk of neurodegenerative disorders such as Alzheimer’s disease. Resveratrol (RSV), a polyphenol with anti-inflammatory, antioxidant, and neuroprotective properties, has been associated with aging prevention by reducing oxidative stress. This in vivo study aimed to determine whethe...
The objective of this study was to evaluate the impact of Terminalia catappa powder consumption on biochemical, morphometric, cardiovascular risk, and hepatic markers in aged Wistar rats. Three groups were formed (n = 10): the control group (CG) was treated with distilled water, and the P500 and P1000 groups were treated with 500 and 1000 mg/kg of Terminalia catappa powder, respectively. Animal body weight and food intake were...
The Cerrado biome, spanning ~2 million km 2 , is one of the most extensive and biodiverse tropical savannas, yet it is paradoxically dominated by only 30 hyperdominant tree species (~2% of all species, > 50% of all stems). However, their vulnerability to climate change and the effectiveness of current conservation efforts remain uncertain. By combining (i) species distribution models calibrated with edaphic‐climatic predictors...
Capsaicin suppresses LPS-induced inflammatory responses via NLRP3/CASP-1/IL-1β axis and purinergic pathways in BV-2 microglial cellsNARA Subscribed
Microglial activation drives neuroinflammation, a key factor in many neurological diseases. The purinergic system is a major regulator of inflammatory responses and represents a promising target for controlling neuroinflammation. Capsaicin, a bioactive compound found in chili peppers, exhibits significant anti-inflammatory and antioxidant properties. This study aimed to investigate the modulatory effects of capsaicin on microg...